Study on Temperature Regulation of Lactic Acid Bacteria Using Metabolic Flux Analysis
Fermentation studies of lactic acid bacteria Rennanqilyf13 were performed to evaluate the potential impacts of culture temperature on cell growth and the production of L-Lactic acid. Quantitative analysis of several metabolic intermediates using metabolic flux analysis (MFA) revealed fluxes during the L-Lactic acid production from glucose. According to the metabolic flux from glucose to L-lactic acid, using different temperature at different fermentation stage maximized the concentration, yield and productivity of L-lactic acid.
Hexing Li, Qunjie Xu and Daquan Zhang
X. J. Xiong and Y. F. Li, "Study on Temperature Regulation of Lactic Acid Bacteria Using Metabolic Flux Analysis", Advanced Materials Research, Vols. 356-360, pp. 127-132, 2012