The cadmium (Cd) stress to xylophyta Vitex negundo var. heterophylla including growth responses and Cd accumulation in plant was investigated in pot experiment with different Cd concentrations. The result indicated that the shoot length, shoot diameter and root diameter as well as the biomass of organs were obviously decreased when Cd was 50 mg/kg. 100 mg/kg Cd caused the chlorosis of the leaf. The accumulated ability of Cd in Vitex negundo var. heterophylla in turn was root > leaf > shoot. This plant presented efficient ability in removing the Cd from the contaminated soil when initial Cd in the soil was 20 mg/kg.