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Synthesis of Lipid-Quantum Dots and the Fluorescence Resonance Energy Transfer of Quantum Dots in Lipid Bilayer

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Abstract:

Hydrophilic CdTe and NIR CdHgTe QDs were successfully transferred from aqueous solution to nonpolar chloroform solvent via efficient phase transfer reagent to synthesize lipid-QDs. The liposomes showed bright fluorescence under the fluorescence microscope. It was confirmed that fluorescence resonance energy transfer (FRET) occurred between two types of QDs encapsulated in lipid bilayer with an excitation wavelength of 370nm, and the FRET efficiencies were satisfied (quenching efficiency was 51% and enhance efficiency was 40%), which laid a foundation for the research of drug release from liposomes.

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Periodical:

Advanced Materials Research (Volumes 399-401)

Pages:

646-649

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.399-401.646

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Online since:

November 2011

Authors:

Chao Ye, Chen Gui Li, Yun Qing Wang, Jie Yu, Fang Zhou, Yu Zhu Hu

Keywords:

Fluorescence Resonance Energy Transfer (FRET), Hydrophilic Quantum Dots (QDs), Liposomes, Near-Infrared (NIR)

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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