Fabrication and Reaction Efficiency Evaluation of Nano/Micro Structure with Carbon Nanotubes for Micro Bio Analysis

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In this study, carbon nanotubes (CNTs) are anticipated as nano/micro structured reaction field for micro Bio-Analysis. CNTs reaction field were made on quartz glass substrate using chemical vapor deposition and Self-Organization of CNTs. To evaluate and reveal the optimal structure of CNTs structure, protein adsorption characteristics were evaluated by fluorescence and transmitting spectroscopy analysis. By fluorescence analysis, it is revealed that proteins tend to adsorb to tip of CNTs structure and finer structure. Finally, protein adsorption was detected as a change of transmissivity of CNTs reaction field, and its detection limit was about 100 nmol/l. Time for analysis was greatly shortened by using transmitting spectroscopy.

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Advanced Materials Research (Volumes 403-408)

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1146-1152

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November 2011

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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[1] S. Iijima, Nature 354, (1991), 56.

Google Scholar

[2] H. Zhang, J. Tang, P. Zhu, J. Ma, L.C. Qin, High tensile modulus of carbon nanotube nano-fibers produced by dielectrophoresis, Chemical Physics Letters 478, (2009), 230-233.

DOI: 10.1016/j.cplett.2009.07.091

Google Scholar

[3] W. A. De Heer, et al., Science 270, (1995), 1179.

Google Scholar

[4] J. Okuno, K Maehashi, K. Matsumoto, K. Kerman, Y. Takamura, E. Tamiya, Single walled carbon nanotubes- arrayed microelectrode chip for electrochemical analysis, Electrochemistry Communications 9, (2007), 13-18.

DOI: 10.1016/j.elecom.2006.07.046

Google Scholar

[5] P. E. lopes, F. V. Hattum, C. M. C. Pereira, P. J. R. O. Növoa, S. Forero, F. Hepp, L. Pambaguian, High CNT content composites with CNT buckypaper and epoxy resin matrix: Impregnation behavior composite production and characterization, Composite Structures 92, (2010).

DOI: 10.1016/j.compstruct.2009.11.003

Google Scholar

[6] T. Becker, S. Mühlberger, C. Bosch-v. Braumühl, G. Müller, A. Meckes, W. Benecke, Microreactors and microfluidic systems: an innovative approach to gas sensing using tin oxide-based gas sensors, Sensors and Actuators B 77, (2001), 48-54.

DOI: 10.1016/s0925-4005(01)00671-2

Google Scholar

[7] A. Splinter, J. St: ürmann, O. Bartels, W. Benecke, Micro membrane reactor: a flow-ghrough membrane for gas pre-combustion, Sensors and Actuators B 83, (2001), 169-174.

DOI: 10.1016/s0925-4005(01)01036-x

Google Scholar

[8] R. Kobayashi, M. Yang, Nanostructured surface by self-assembly of carbon nanotubes for bio-analysis, Journal of Solid Mechanics and Materials Engineering vol. 3 No. 2, (2009), 366-374.

DOI: 10.1299/jmmp.3.366

Google Scholar

[9] S. Sivaramakrishnan, R. Rajamani, C. S. Smith, K.A. McGee, K.R. Mann, N. Yamashita, Carbon nanotube-coated surface acoustic wave sensor for carbon dioxide sensing, Sensors and Actuators B 132, (2008), 296-304.

DOI: 10.1016/j.snb.2008.01.041

Google Scholar

[10] H. M. Cheng, F. Li, G. Su, H. Y. Pan, L.L. He, X. Sun, M.S. Dresselhaus, Large-scale and low-cost synthesis of single-walled carbon nanotubes by the catalytic pyrolysis of hydrocarbons, Applied Physics Letters 72, (1998), 3282-3284.

DOI: 10.1063/1.121624

Google Scholar

[11] T. Yabe, M. Yang, Surface modification and density control of carbon nanotubes by Ar plasma irradiation, International Journal of material Forming, Proceeding of AMPT2010, (2010), CD-ROM.

Google Scholar