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Preliminary Evaluation of Antimicrobial and Cytotoxic Activities of Extracts from Actinidia macrosperma

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Abstract:

The petroleum ether, chloroform, ethyl acetate, n-hexane and aqueous successive extracts from the stems of Actinidia macrosperma C. F. Liang have been screened for antibacterial and antifungal activities in vitro using the disc diffusion method, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC)/minimum fungicidal concentration (MFC). General toxicity of these extracts has also been assessed by brine shrimp lethality assay. The chloroform extract exhibited the most significant antimicrobial (MIC in the range of 60–500μg/ml, MBC in the range of 150–1000μg/ml, MFC in the range of 170–600μg/ml) and cytotoxic activities (LC50=16.82μg/ml at 24 hours).

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Periodical:

Advanced Materials Research (Volumes 455-456)

Pages:

1200-1203

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.455-456.1200

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Online since:

January 2012

Authors:

Yin Lu, Yun Peng Zhao, Cheng Xin Fu

Keywords:

Actinidia macrosperma, Antimicrobial Activity, Brine Shrimp, Cytotoxicity

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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