Evaluation and Prediction of Mixture Toxicity of PFOS and PFOA to Zebrafish (Danio rerio) Embryo

Guang Hui Ding; Jing Zhang; Man Wang; Yi Hong Chen; Guo Yi Luo; De Qi Xiong

doi:10.4028/www.scientific.net/AMR.485.297

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Research of the Relation between the Industry Structure and Carbon Emissions in China
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Porous Silicon Biosensor for the Detection of Transgenic Cotton of Antifeezing Protein
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The Perspectives of Magnetic Fluid Deformable Mirrors for Adaptive Optics Systems
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Evaluation and Prediction of Mixture Toxicity of PFOS and PFOA to Zebrafish (Danio rerio) Embryo
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Study on Solid-State Anaerobic Co-Digestion with Distiller’s Grains and Food Waste for Methane Production
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 485Evaluation and Prediction of Mixture Toxicity of...

Evaluation and Prediction of Mixture Toxicity of PFOS and PFOA to Zebrafish (Danio rerio) Embryo

Abstract:

Perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) have emerged as two concerning contaminants in recent years. However, there is limited information about their mixture toxicity to aquatic organisms. In the present study, the single and mixture toxicity of PFOA and PFOS to zebrafish (Danio rerio) embryo were tested, and the mixture toxicity was predicted by concentration addition (CA) and independent action (IA) models. It is found that PFOS and PFOA have synergistic effect at 96 hpf, while this kind of synergistic effect is not obvious at 72 hpf. CA and IA models both could predict the 72 h mixture toxicity, while underestimate the 96 h mixture toxicity.

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Advanced Materials Research (Volume 485)

Pages:

297-300

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.485.297

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Online since:

February 2012

Authors:

Guang Hui Ding, Jing Zhang, Man Wang, Yi Hong Chen, Guo Yi Luo, De Qi Xiong

Keywords:

Mixture Toxicity, PFOA, PFOS, Zebrafish (Danio rerio) Embryo

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