The Antioxidative Activity and the Fingerprint by HPLC of the Flavonoids of Astragalus mongholicus

Abstract:

The flavonoids of eight samples of Huangqi, the roots of Astragalus mongholicus, have been analyzed. The concentration of total flavonoids from different samples of Astragalus Mongholicus, was about 0.5mg/g~1.0mg/g, according to the rutin standard substance. Then the fingerprints were set up and four flavonoids were identified as Calycosin-7-O-β-D-glucoside, 7-Hydroxy-4'-methoxyisoflavone, 7,3'-dihydroxy-4'-methoxyisoflavone and Formononetin-7-O-β-D-glucoside by liquid chromatography. Moreover, the antioxidative activity of flavonoids extractive from Astragalus Mongholicus was also studied and the IC₅₀ of Astragalus flavonoids extractive for scavenging ATBS+ free radical and DPPH•free radical were 0.61 mg/mL and 4 mg/mL respectively

• Periodical: Advanced Materials Research (Volumes 550-553)
• Pages: 1637-1642
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.550-553.1637
• Online since: July 2012
• Authors: Guang Xiang Zeng, Hai Yan Ou, Qing Yi Wei, Zheng Xiang Ning
• Keywords: Antioxidative Activity, Astragalus mongholicus, Fingerprint, Flavonoid

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