Synthesis of New Phenoxypropylamines and Evaluation of their Antiulcer Activity as H2 -Receptor Antagonist

Hui Zhang; Min Fan Wu; Yu Tian; Jian Tong; Li Hong Shang

doi:10.4028/www.scientific.net/AMR.554-556.1849

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 554-556Synthesis of New Phenoxypropylamines and...

Synthesis of New Phenoxypropylamines and Evaluation of their Antiulcer Activity as H₂ -Receptor Antagonist

Abstract:

More new phenoxypropylamines have been synthesized. All the products have been characterized by elemental analysis, 1H-NMR, ¹C-NMR and MS. The biological activity effects of the title compounds were examined. From the biological activity re^{Superscript text}sults, we found that some of them showed significant gastric acid antisecretory activity.

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Periodical:

Advanced Materials Research (Volumes 554-556)

Pages:

1849-1852

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.554-556.1849

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Online since:

July 2012

Authors:

Hui Zhang, Min Fan Wu, Yu Tian, Jian Tong, Li Hong Shang

Keywords:

Antiulcer Agents, Biological Activity, Phenoxypropylamines, Roxatidine, Synthesis

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References

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