Synthesis and Antibacterial Activity of some New Quinoxaline-1,4-Dioxide Derivatives

Zhi Jun Xin; Jian Ping Liang; Xue Hu Li; Lei Tao; Xi Hong Lu

doi:10.4028/www.scientific.net/AMR.634-638.1376

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Synthesis and Antibacterial Activity of some New Quinoxaline-1,4-Dioxide Derivatives
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The MRTF Induced the Migration of Colon Cancer HT-29 Cell
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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 634-638Synthesis and Antibacterial Activity of some New...

Synthesis and Antibacterial Activity of some New Quinoxaline-1,4-Dioxide Derivatives

Abstract:

As a continuation of our research and with the aim of obtaining new antibacterial agents which can improve the current chemotherapeutic antibacterial treatments, a series of quinoxaline-1,4-di-N-oxide derivatives were synthesized and evaluated for antibacterial activity against bacterial growing in macrophages in vitro. The results indicate that the new compounds exhibited a good antibacterial activity. Also, the potency and low toxicity of these compounds make them valid leads for synthesizing new compounds that possess better activity.

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Periodical:

Advanced Materials Research (Volumes 634-638)

Pages:

1376-1379

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.634-638.1376

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Online since:

January 2013

Authors:

Zhi Jun Xin, Jian Ping Liang, Xue Hu Li, Lei Tao, Xi Hong Lu

Keywords:

Antibacterial Activity, Quinoxaline-1,4-Dioxide Derivatives, Synthesis

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