The MRTF Induced the Migration of Colon Cancer HT-29 Cell

Yong Jiang; Hui Yan Wang; Jian Hui Cai; Feng Hao; Su Hong Guo; Zhong Hai Yuan; Yan Li; Yi Ju Hou; Lei Liu; Lei Zhang; Yan Li

doi:10.4028/www.scientific.net/AMR.634-638.1384

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 634-638The MRTF Induced the Migration of Colon Cancer...

The MRTF Induced the Migration of Colon Cancer HT-29 Cell

Abstract:

Tumor is a kind of disease with higher morbidity and mortality, which is currently a serious threat to human health, and to strengthen the prevention and treatment of neoplastic diseases has important economic and social benefits. The migration behavior of tumor cell is a key link in the process of tumor metastasis. In this study, the related cellular and molecular mechanisms of MRTF and AQP1 inducing the migration of colon cancer cells HT-29 were revealed in the respect of Gene transcription regulation. This heralded that MRTF and AQP1 could probably be a new target on treating the tumor cell migration.

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Periodical:

Advanced Materials Research (Volumes 634-638)

Pages:

1384-1387

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.634-638.1384

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Online since:

January 2013

Authors:

Yong Jiang, Hui Yan Wang, Jian Hui Cai, Feng Hao, Su Hong Guo, Zhong Hai Yuan, Yan Li, Yi Ju Hou, Lei Liu, Lei Zhang, Yan Li

Keywords:

Cell Migration, Colon Cancer

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