Coaled Carbon-Based Solid Acid: a New and Efficient Catalyst for Click Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones under Solvent-Free Conditions

Abstract:

Coaled carbon-based solid acid (CCBSAC) is reported as a new, efficient and recyclable catalyst for the regioselective multicomponent synthesis of dihydropyrimidin-2(1H)-ones from aldehydes, β-ketoesters and urea or thiourea under solvent-free conditions. The structure and thermal stability of CCBSAC which resulted from ultra-clean coal resources mainly were characterized by IR, XRD, and TG. Nineteen dihydropyrimidin-2(1H)-ones examples were prepared and this catalyst could recycle up to 4 consecutive runs without losing its efficiency. The high yields of products, short reaction times, ease of work-up and clean procedure will make the present method a useful and important addition to the previous methodologies for the synthesis of dihydropyrimidin-2(1H)-ones.

• Periodical: Advanced Materials Research (Volumes 634-638)
• Pages: 504-507
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.634-638.504
• Online since: January 2013
• Authors: Wan Yi Liu, Ning Liu, Rui Yuan Zheng, Bing Li, Xia Zhang, Shi Jiao Liang, Zheng Wang
• Keywords: Biginelli Reaction, Coaled Carbon-Based Solid Acid, Dihydropyrimidin-2(1H)-Ones, Sulfonation, Ultra-Low Ash Taixi Coal

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