Limit Test of Aristolochic Acid a in YishenJuanbi Pill

Abstract:

We developed a HPLC method with high specificity and sensitivity for the limit test of AAA in Yishen Juanbi Pill. In this mothod, the detection limit for AAA was 2.216ng. AAA could not be detected in all the 3 batches of the pill which suggests that the pill prepared by the modified water extraction and ethanol precipitation method is safe for clinical use.This efficient HPLC technique is also proposed for the limit test of AAA in other preparations besides Yishen Juanbi Pill.

• Periodical: Advanced Materials Research (Volumes 634-638)
• Pages: 991-995
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.634-638.991
• Online since: January 2013
• Authors: Xing Cui Qu, Li Ma, Feng Han, Jing Gao
• Keywords: AAA, High Performance Liquid Chromatography (HPLC), Limit Test, Yishen Juanbi Pill

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