Excellent Preparation of Azetidin-3-Ones from Propargylic Alcohols by Gold-Catalysis

Abstract:

Azetidin-3-ones are important heterocycles in organic synthesis and pharmaceutical chemistry. With gold-catalyzed alkyne intermolecular oxidation, these versatile heterocycles can be prepared in three steps from readily available propargylic alcohols with high efficiencies.

• Periodical: Advanced Materials Research (Volumes 634-638)
• Pages: 970-974
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.634-638.970
• Online since: January 2013
• Authors: Ping Tan, Jian Nan Xiang
• Keywords: Alkyne, Azetidin-3-One, Carbenes, Cyclization, Gold

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