Preparation and Characterization of Broad-Spectrum Sunscreens Loaded Nanostructured Lipid Carrier

Yan Ling Chen; Qiang Xia

doi:10.4028/www.scientific.net/AMR.669.67

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 669Preparation and Characterization of Broad-Spectrum...

Preparation and Characterization of Broad-Spectrum Sunscreens Loaded Nanostructured Lipid Carrier

Abstract:

A comprehensive photoprotective formulation was developed to enhance photoprotection ,compared to a conventional nanoemulsion ,having the concentration of two new molecular sunscreens, namely Diethylamino hydyoxybenzoyl hexyl benzoate(Uvinul ® A Plus) and Ethylhexyl triazone(Uvinul® T 150). In the present paper, the sunscreen mixture was incorporated into nanostructured lipid carriers (NLCs). After the production by hot high pressure homogenization, the NLC were analyzed in terms of particle size, physical state, particle shape, ultraviolet absorbance and stability. The particle size for all NLC was around 100-900 nm after production. The determination of 2 organic UV filters was performed by HPLC with UV spectrophotometric detection. The loading capacities for molecular sunscreens was up to 30%. In the sunlight, the retention rate of Uvinul ® A Plus and Uvinul ® T150 was still up to 80% after three months .

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Periodical:

Advanced Materials Research (Volume 669)

Pages:

67-71

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.669.67

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Online since:

March 2013

Authors:

Yan Ling Chen, Qiang Xia

Keywords:

Diethylamino Hydyoxybenzoyl Hexyl Benzoate, Ethylhexyl Triazone, High Performance Liquid Chromatography (HPLC), Nanostructured Lipid Carriers, Retention Rate

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