Photothermal Imaging (PTI) System for the Imaging of Gold Nano-Particles and Cellular Organelles

Chi Lok Wong; George C.K. Chen; Teu Choon Kiat; Srivathsan Vasudevan; Pham Thuy Anh; Niladri Bihari Puhan; Marta Andika; Shuchi Agarwal; Zhi Ping Lin; Chen Peng

doi:10.4028/www.scientific.net/AMR.74.45

Paper Titles

A Transient Simulation for Analysis of Volume Transition of pH-Sensitive Hydrogel in Micro-Channel
p.25

Analysis of Microelectromechanical Systems Using the Meshless Random Differential Quadrature Method
p.29

Mathematical Modeling of Hydrogels for Microfluidic Flow Control
p.33

All-Optical Signal Processing Based on Nonlinear Effects in Semiconductor Optical Amplifiers
p.39

Photothermal Imaging (PTI) System for the Imaging of Gold Nano-Particles and Cellular Organelles
p.45

The Design and Fabrication of Poly(dimethylsiloxane) Single Mode Rib Waveguides for Lab-on-a-Chip Applications
p.51

Analysis of Novel Building Blocks for Photonic MEMS Based on Deep 1D Photonic Crystals
p.55

A THz-Wave Generator Based on MEMS Technology
p.59

A Photonic MEMS Polarization Switch
p.63

HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 74Photothermal Imaging (PTI) System for the Imaging...

Photothermal Imaging (PTI) System for the Imaging of Gold Nano-Particles and Cellular Organelles

Abstract:

Photo-thermal imaging (PTI) is an imaging technique that can provide a resolution exceeding the diffraction limit. The theoretical resolution limit is less than 1 nm, therefore it is particularly suited to analyse particles in nano-size targets. It is also a non-labelling, high temporal resolution technique that can be conducted in a normal live cell environment. In this paper, a PT imaging microscopy system has been demonstrated and the integrity of the system is verified through a series of experiments on different samples, including red polystyrene bead and carbon nano-tube. The PTI technique can find further applications in biology studies for the visualization of cell organelles and apoptosis studies.