The Influence of Amount of Succinic Anhydride in Chain Extension Reaction on Increasing Molecular Weight of Poly(lactic acid)

Chaichana Piyamawadee; Duangdao Aht-Ong

doi:10.4028/www.scientific.net/AMR.747.148

Paper Titles

Fabrication of Shellac-Based Effervescent Floating Matrix Tablet as a Novel Carrier for Controlling of Drug Release
p.135

Behaviour of Lipid-Based Formulations Containing Nifedipine in Aqueous Media as Observed by Small Angle X-Ray Scattering
p.139

Preparation of Solid Self-Emulsifying Drug Delivery System of Manidipine Hydrochloride
p.143

PEG-Glu-PEI-Dexamethasone Conjugates: Synthesis, Characterization and In Vitro Gene Transfer Properties
p.147

The Influence of Amount of Succinic Anhydride in Chain Extension Reaction on Increasing Molecular Weight of Poly(lactic acid)
p.148

The Recovery Effect of the Translationally Controlled Tumor Protein in 2-Hydroxy-Ethyl Methacrylate-Treated Human Dental Pulp Cells
p.153

Influence of Bagasse Carboxymethyl Cellulose Addition on the Thermal and Mechanical Properties of PLA Composites
p.157

Dissolution Improvement of Itraconazole by a Nanoparticulate System Containing Lecithin-Pectin Complexes
p.162

Fabrication and Antifungal Activity of Cellulose Acetate-Based Fibers Encapsulating Natural Neem Seed Oil
p.166

HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 747The Influence of Amount of Succinic Anhydride in...

The Influence of Amount of Succinic Anhydride in Chain Extension Reaction on Increasing Molecular Weight of Poly(lactic acid)

Abstract:

High molecular weight PLA was successfully synthesized by chain extension reaction of hydroxylated prepolymer using succinic anhydride as a chain extender. Hydroxylated prepolymer was prepared by direct condensation polymerization of L-lactic acid in the presence of 1,4-butanediol. Various molar ratios between hydroxylated prepolymer and succinic anhydride (i.e, 1:1, 1:2, 1:3) were investigated. The results showed that succinic anhydride can help increasing molecular weight of hydroxylated prepolymer approximately up to 47% as characterized by gel permeation chromatography (GPC) technique. Proton nuclear magnetic resonance (¹H-NMR) was used to investigate structure of chain-extended PLA. Differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) were used to examine thermal properties while the crystallinity was investigated by X-ray diffraction (XRD).

You might also be interested in these eBooks

Multi-Functional Materials and Structures IV

View Preview

Info:

Periodical:

Advanced Materials Research (Volume 747)

Pages:

148-152

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.747.148

Citation:

Cite this paper

Online since:

August 2013

Authors:

Chaichana Piyamawadee, Duangdao Aht-Ong

Keywords:

Chain Extender, Chain Extension Reaction, Direct Condensation Polymerization, Poly(lactic acid) (PLA), Succinic Anhydride

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] J. Kylma, J. Touminen, A. Helminen, J. Seppala, Chain extending of lactic acid oligomers. Effect of 2, 2'-bis(2-oxazoline) on 1, 6-hexamethylene diisocyanate linking reaction, Polymer 42 (2001) 3333-3343.

DOI: 10.1016/s0032-3861(00)00751-5

Google Scholar

[2] K. Noibuddee, Y. Sritana-anant, V. Tangpasuthadol, Molecular Weight Enhancement by Chain Extension of Poly(lactic acid) Derived from Polycondensation, PCT-2, Bangkok (2011).

Google Scholar

[3] J.B. Zeng, Y.D. Li, Q.Y. Zhu, K. K Yang, Y.Z. Wang, A novel biodegradable multiblock poly(ester urethane) containing poly(L-lactic acid) and poly(succinate) blocks, Polymer 50 (2009) 1178-1186.

DOI: 10.1016/j.polymer.2009.01.001

Google Scholar

[4] K.W. Kim, S.I. Woo, Synthesis of High-Molecular-Weight Poly(L-lactic acid) by Direct Polycondensation, Macromol Chem Phys 203 (2002) 2245-2250.

DOI: 10.1002/1521-3935(200211)203:15<2245::aid-macp2245>3.0.co;2-3

Google Scholar