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Preparation and Characterization of Sodium Alginate-Polyvinyl Alcohol Wound Dressing System Containing Ciprofloxacin Hydrochloride

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Abstract:

Sodium alginate (SA)/polyvinyl alcohol (PVA) matrix-based wound dressing system containing ciprofloxacin hydrochloride, a topical anti-infective drug, were obtained by a casting/solvent evaporation method. The FTIR spectrum indicated that a strong interaction between SA and PVA and a good compatibility between ciprofloxacin hydrochloride and SA/PVA. The surface contact angles showed that the SA/PVA membrane has good compatibility. The water absorption and water retention rate increased when the concentration of PVA increased. The swelling ratio of SA/PVA mixtures indicated that the membrane go to balance in about 30min. Moreover, the release rate of ciprofloxacin hydrochloride was found to be increased with the increment of PVA content for all the composite samples. Thus, SA/PVA wound dressing systems containing ciprofloxacin hydrochloride could be a novel approach in wound care.

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Periodical:

Advanced Materials Research (Volume 749)

Pages:

388-393

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.749.388

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Online since:

August 2013

Authors:

Zhao Qing Li, Zhen Li, Hong Zhao, Wei Zheng, Li Li

Keywords:

Ciprofloxacin Hydrochloride, Drug Release, PVA, Sodium Alginate, Wound Dressing

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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References

[1] Yuki Hori, Amy M. Winans, Darrell J. Irvine: Acta Biomaterialia. Vol. 5 (2009), p.969–982.

Google Scholar

[2] M. George, T. Emilia Abraham: J CONTROL RELEASE. Vol. 114 (2006), p.1–14.

Google Scholar

[3] P. Arockianathan, S. SEKAR, S. SANKAR: CARBOHYD POLYM. Vol. 90 (2012), pp.717-724.

Google Scholar

[4] J. Kim, J. Park, et al: INT J PHARM. Vol. 359 (2008), p.79–86.

Google Scholar

[5] Y. HORI, AMY M. WINANS, C. C. HUANG, et al: BIOMATERIALS. Vol. 29(2008), p.3671–3682.

Google Scholar

[6] F. STOPS, J. T. FELL, J. H. COLLETT, et al: INT J PHARM. Vol. 350 (2008), p.301–311.

Google Scholar

[7] C. CHRETIEN, V. BOUDY, P. ALLAIN, et al: J CONTROL RELEASE. Vol. 96(2004), p.369– 378.

Google Scholar

[8] Eng-Seng Chan: CARBOHYD POLYM . Vol. 84 (2011), pp.1267-1275.

Google Scholar

[9] Z.X. Meng, X.X. Xu, W. Zheng, et al: COLLOID SURFACE B. Vol. 84(2011) p.97–102.

Google Scholar

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