Preparation and Characterization of Graft Copolymerization of Methyl Methacrylate onto Chitosan

Abstract:

To prepare and optimize core-shell nanoparticles consisting of poly (methyl methacrylate) (PMMA) with tert-butylhydroperoxide (TBHP) as an initiator. Methods The core-shell nanoparticles consisting of poly (methyl methacrylate) (PMMA) cores surrounded by various of chitosan shells, induced by tert-butylhydroperoxide (TBHP) solution. The average particle diameter and zeta potential of chitosan nanoparticles were determined by Zetasizer nanoanalyzer.Atomic force microscope was used to analyse core-shell nanoparticles morphology . Results The concentrations of chitosan and initiator tert-butylhydroperoxide (TBHP) and amounts of monomer methyl methacrylate (MMA),reaction time were effects on the nanoparticle size and grafting efficiency. The optimal conditions as follows: 0.25g in 47mL 1% acetic acid solution, tert-butylhydroperoxide (TBHP) 0.3mL, methyl methacrylate (MMA) 1g, reaction time 1.5 h and reaction temperature was at 80°C. Conclusion CS-g-PMMA nanoparticles could be successfully prepared by polymerizing MMA onto CS using tert-butylhydroperoxide as an initiator.

• Periodical: Advanced Materials Research (Volumes 785-786)
• Pages: 455-458
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.785-786.455
• Online since: September 2013
• Authors: Bi Ying Sha, Qing Shan Liu, Ling Zhang, Xiao Ying Yin
• Keywords: Characterization, Chitosan, Core-Shell Nanoparticles, Grafted, PMMA

References

[1] Peter M. Applications and environmental aspects of chitin and chitosan. J Macromol Sci Pure Appl Chem 1995; A32: 629–40.

[2] Ravi Kumar, M.N.V., Muzzarelli, R.A.A., Muzzarelli, C., Sashiwa, H., Domb, A.J., Chitosan chemistry and pharmaceutical perspectives, Chem. Rev. 2004, 104, 6017-6084.

DOI: 10.1021/cr030441b

[3] Gerrit Borchard. Chitosans for gene delivery. J Advanced Drug Delivery Reviews 2001, 52: 145–150.

DOI: 10.1016/s0169-409x(01)00198-3

[4] Xiang Li, Zhuangqi Cao, Qishun Shen , Yanfang Yang . Influence of dopant concentration on thermo-optic properties of PMMA composite[J]. Materials Letters, 2006, 60: 1238–1241.

DOI: 10.1016/j.matlet.2005.11.005

[5] RICHARD YOUNG, MALGORZATA DUKAT. Stimulus Properties of PMMA: Effect of Optical Isomers and Conformational Restriction[J]. Pharmacology Biochemistry and Behavior, 1999, 64, (2): 449–453.

DOI: 10.1016/s0091-3057(99)00060-x

[6] Hengyi Wu, Gang Ma, Yuanming Xia. Experimental study of tensile properties of PMMA at intermediate strain rate[J]. Materials Letters , 2004, 58: 3681–3685.

DOI: 10.1016/j.matlet.2004.07.022

[7] Magnus Jonsson , Ove Nordin , Eva Malmstrom , Claes Hammer. Suspension polymerization of thermally expandable core/shell particles[J]. Polymer , 2006, 47: 3315–3324.

DOI: 10.1016/j.polymer.2006.03.013

[8] Li, P., Zhu, J., Sunintaboon, P., & Harris, F. W. Graft copolymerization of methyl methacrylatefrom water-soluble polymer chains containing amino groups. Langmuir, 18(22), (2002)8641–8646.

DOI: 10.1021/la0261343

[9] V.R. Sinha, A.K. Singla. Chitosan microspheres as a potential carrier for drugs International Journal of Pharmaceutics 274 (2004) 1–33.

[10] Yushan Liu, Peng Liu, Zhixing Su. Core-shell attapulgite@polyaniline composite particles viain situ oxidative polymerization[J]. Synthetic Metals 157 (2007) 585–591.

DOI: 10.1016/j.synthmet.2007.06.009

[11] M. OkuboU, J. Izumi. Synthesis of micron-sized monodispersed, core-shellcomposite polymer particles by seeded dispersion polymerization[J]. Physiochemical and Engineering Aspects 153(1999) 297-304.

DOI: 10.1016/s0927-7757(98)00450-6