Morphological Characterization of Chitosan in the Hydroxyapatite/Chitosan Nanocomposites

Abstract:

The morphological differences of chitosan (CS) in the hydroxyapatite (HA)/CS nanocomposites were investigated in detailed, which were prepared via in situ hydrothermal precipitation. The results show that the obtained nanocomposites have excellent crystallinity and the crystal has excellent ordered structure, which is important to the composites performances in the biomedical application. Moreover, the CS arrangement and crystallinity in the composites greatly depend on the hydrothermal temperature and the pH value of precipitating agent. The temperature ranging from 373 to 413K and pH value of precipitating agent ranging from 12 to 14 were favorable to the crystallization and oriented growth of CS molecules in the composites. The CS crystals with better arrangement are assembled in the order of layer-by-layer in these composites.

• Periodical: Advanced Materials Research (Volumes 79-82)
• Pages: 1675-1678
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.79-82.1675
• Online since: August 2009
• Authors: Xiao Ying Lu, Xiu Hong Wang, Jian Xin Wang, Shu Xin Qu, Jie Weng
• Keywords: Chitosan (CS), Hydrothermal Treatment, Hydroxyapatite (HAP), Morpholoy, Nanocomposite

References

[1] P.J. VandeVord, H.W. Matthew, S.P. DeSilva, L. Mayton, B. Wu and P.H. Wooley: J. Biomed. Mater. Res. Vol. 59 (2002), p.585.

DOI: 10.1002/jbm.1270

[2] E.M. Oomsa, J.G.C. Wolkea, M.T.V. de Heuvelb, B. Jeschke and J.A. Jansen: Biomaterials Vol. 24 (2003), p.989.

[3] M. Atsushi, I. Toshiyuki, K. Hisatoshi and T. Tanaka:J. Mater. Sci. Eng. C Vol. 4 (2004), p.723.

[4] E. Ciftci, M.N. Rahaman and M. Shumsky: J. Mater. Sci. Vol. 36 (2001), p.4875.

[5] H.P. Klug and L.E. Alexander: X-ray Diffraction Procedures for Polycrystallite and Amorphous Materials (Wiley Publication, New York 1974).

[6] X.Y. Lu, X.H. Wang, S.X. Qu and J. Weng: J. Inorg. Mater. Vol. 2 (2008), p.332.

[7] Y.Q. Zhang, CH.H. Xue, Y. Xue, R. CH. Gao and X.L. Zhang: Carbohydr. Res. Vol 340 (2005), p. (1914).

[8] T.D. Jiang: Chitosan (Chinese Chemical Industry Press, BeiJing 2001).

[9] T. Yui, K. Imada, K. Okuyama, Y. Obata and K. Suzuki: Macromolecules Vol. 27 (1994), p.7601.

[10] K. Okuyama, K. Noguchi, M. Kanenari, T. Egawa and K. Osawa: Carbohydr. Polym. Vol. 3 (2000), p.237.

[11] Y. Isamu, I. Soichiro and S. Masumi: Biomaterials Vol. 24 (2003), p. (2031).