Microbial Hydroxylation of Progesterone with Aspergillus ustus

Tian Chao Lai; Yun Dai; Bin Zhou; Guang Jian Shen; Hai Lin Su; Gang Du

doi:10.4028/www.scientific.net/AMR.807-809.410

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 807-809Microbial Hydroxylation of Progesterone with...

Microbial Hydroxylation of Progesterone with Aspergillus ustus

Abstract:

Progesterone was biotransformed by Aspergillus ustus in this paper. Two products were obtained and they were identified as 11α-hydroxyprogesterone and 11α,15β-dihydroxyprogesterone by NMR and MS. The fermentation process of biotransformtion had been studied with HPLC and 11α-hydroxyprogesterone was the main product.

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Periodical:

Advanced Materials Research (Volumes 807-809)

Pages:

410-413

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.807-809.410

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Online since:

September 2013

Authors:

Tian Chao Lai, Yun Dai, Bin Zhou, Guang Jian Shen, Hai Lin Su, Gang Du

Keywords:

Aspergillus ustus, High Performance Liquid Chromatography (HPLC), Progesterone, Transformation

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