Mechanical Adjustment Tissue Engineered Human Auricular Cartilage Shape and Elasticity In Vitro

Abstract:

Purposes: This study is to establish an adjustable environment for culturing the functional human auricular cartilage shape in vitro. Methods: Physical stimulation affects chondrocytes function. Therefore, bioreactors have been designed in vitro to transmit a novel perfussion-compression loading and can stretch and maintain the construct's size and ear-specific shape. Results: It could provide cultures with multimechanical adjustment complex mechanical environment of a normal human auricular cartilage. Conclusions: We propose that this comprehensive perfusion-compression loading bioreactor can enhance the cultivation of shaping and elastic human auricular cartilage constructs in vitro.

• Periodical: Advanced Materials Research (Volumes 816-817)
• Pages: 901-904
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.816-817.901
• Online since: September 2013
• Authors: Wen Kang Li, Hong Li, Yi Zhi Liu, Ling He
• Keywords: Bioreactor, Human Auricular Cartilage, Tissue Engineering

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