Synthesis of Tetrahydropalmatine

Dao Wu Wang; Xiao Long Li; Xin Xia Feng; Jin Long Zheng; Long Zhang

doi:10.4028/www.scientific.net/AMR.850-851.1193

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 850-851Synthesis of Tetrahydropalmatine

Synthesis of Tetrahydropalmatine

Abstract:

Tetrahydropalmatine in overall yield of 18% was synthesized from alkaloids in Coptids Rhizoma with the similar structure of isoquinoline by a three-step reaction of alkaloids preparation, demethylation or demethylene-dioxy, deoxidation, methylation and so on. The structure was confirmed by ¹H-NMR IR and ESI-MS.

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Advanced Materials Research (Volumes 850-851)

Pages:

1193-1196

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.850-851.1193

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Online since:

December 2013

Authors:

Dao Wu Wang, Xiao Long Li, Xin Xia Feng, Jin Long Zheng, Long Zhang*

Keywords:

Alkaloids in Coptids Rhizoma, Drug Rehab, Palmatine, Structure of Isoquinoline, Synthesis

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References

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