The Synthesis of (1-oxaspiro[2.5]octan-2-ylmethoxy)(tert-Butyl) Dimethylsilane

Dong Wang Liu; Lin Jun Tang; Fei Fei Huang; Li Ping Wang; Xiao Ji Wang; Shuang Ping Huang

doi:10.4028/www.scientific.net/AMR.881-883.430

Paper Titles

Glycoconjugation of 4-Methylumbelliferone via “Click Chemistry”
p.414

Chemical Constituents from Gentiana algida Pall
p.419

Synthetic Study towards (±)Ieodomycin A
p.423

Anti-Fatigue Effects of Polysaccharides from Gynostemma pentaphyllum Makino by Forced Swimming Test
p.426

The Synthesis of (1-oxaspiro[2.5]octan-2-ylmethoxy)(tert-Butyl) Dimethylsilane
p.430

Synthesis of (R)-3-((4-methoxybenzyl)oxy)butanal
p.434

Study on Synthesis of (R)-tert-butyl (1-hydroxybut-3-yn-2-yl)carbamate
p.438

Alkaloids from Penicillium oxalicum, a Fungus Residing in Acrida cinerea
p.442

Facile Synthesis, Characterization and Anti-Inflammatory Effect of 3-Aminoindolizine Derivatives
p.446

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 881-883The Synthesis of...

The Synthesis of (1-oxaspiro[2.5]octan-2-ylmethoxy)(tert-Butyl) Dimethylsilane

Abstract:

Venlafaxine (Fig. 1) is a new generation antidepressant drug. (1-oxaspiro [2.octan-2-ylmethoxy)(tert-butyl) dimethylsilane (11) as an important intermediate of (+) or (-) venlafaxine (1), was synthesized by four steps including an key epoxidation.

You might also be interested in these eBooks

Chemical, Material and Metallurgical Engineering III

View Preview

Info:

Periodical:

Advanced Materials Research (Volumes 881-883)

Pages:

430-433

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.881-883.430

Citation:

Cite this paper

Online since:

January 2014

Authors:

Dong Wang Liu, Lin Jun Tang, Fei Fei Huang, Li Ping Wang, Xiao Ji Wang, Shuang Ping Huang

Keywords:

(1-oxaspiro [2.octan-2-ylmethoxy)(tert-butyl) Dimethylsilane, Synthesis, Venlafaxine

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] Subhash P. C., Sumanta G., Kailash P. P. Tetrahedron Letters, vol. 54 (2013), P. 2137.

Google Scholar

[2] (a) Jinpei, Z., Huibin, Z., Xuezhen, H., Wenlong, H. J. Cin. Pharm. Univ. vol. 30 (1999).

Google Scholar

[3] (a) Subhash, P. C.; Sumanta, G.; Garai, P. P. Tetrahedron Letters, vol. 54 (2013), P. 2137. (b)Davies, H. M. L., Ni, A. Chem. Commun. 2006, P. 3110. (c) Bhuniya, R.; Nanda, S. Tetrahedron Letters, vol. 53 (2012), P. (1990).

Google Scholar

[4] A. Srikrishna, P. Praveen Kumar. Tetrahedron, vol. 56 (2000), P. 8189.

Google Scholar