Glycoconjugation of 4-Methylumbelliferone via “Click Chemistry”

Ru Chun Yang; Tao Hu; Ban Peng Cao; Xi Chen; Qiang Xiao

doi:10.4028/www.scientific.net/AMR.881-883.414

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 881-883Glycoconjugation of 4-Methylumbelliferone via...

Glycoconjugation of 4-Methylumbelliferone via “Click Chemistry”

Abstract:

A series of carbohydrate-conjugated 4-methylumbelliferone were synthesized using 1,3-dipolar cycloaddition “click chemistry” of the azide and alkyne. The reaction is straight forward and in high yield. The strategy will be useful for synthesizing glycoconjugated derivatives of natural products.

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Periodical:

Advanced Materials Research (Volumes 881-883)

Pages:

414-418

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.881-883.414

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Online since:

January 2014

Authors:

Ru Chun Yang, Tao Hu, Ban Peng Cao, Xi Chen, Qiang Xiao*

Keywords:

4-Methylumbelliferone, Click Chemistry, Conjugation, Natural Products

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References

[1] G. M. Cragg, D. J. Newman and K.M. Snader: Journal of Natural Products Vol. 60 (1997), p.52.

Google Scholar

[2] D. J. Newman, G. M. Cragg and K.M. Snader: Journal of Natural Products Vol. 66 (2003), p.1022.

Google Scholar

[3] M. S. Butler: Journal of Natural Products Vol. 67 (2004), p.2141.

Google Scholar

[4] J. Wu, S. Zhang, Q. Xiao, J.S. Huang, L.J. Long and L.M. Huang: Tetrahedron Letters Vol. 45 (2004), p.591.

Google Scholar

[5] J. Wu, Q. Xiao, S. Zhang, X. Li, Z.H. Xiao, H.X. Ding and Q.X. Li: Tetrahedron Vol. 61 (2005), p.8382.

Google Scholar

[6] J. Stuben, B. Bertram and M. Wiessler: International Journal of Oncology Vol. 7 (1995), p.225.

Google Scholar

[7] D. F. Wyss, J. S. Choi, J. Li, M.H. Knoppers, K.J. Willis, A.R. Arulanandam, A. Smolyar, E.L. Reinherz and G. Wagner : Science Vol. 269 (1995), p.1273.

DOI: 10.1126/science.7544493

Google Scholar

[8] L. Vertesy, H. W. Fehlhaber and A. Schulz: Angewandte Chemie-International Edition in English Vol. 33 (1994), p.1844.

Google Scholar

[9] E. Penalver, L. Ojeda, E. Moreno and R. Lagunas: Yeast Vol. 13 (1997), p.541.

Google Scholar

[10] H. C. Kolb, M. G. Finn and K.B. Sharpless: Angewandte Chemie-International Edition Vol. 40(2001), (2004).

Google Scholar

[11] H. C. Kolb and K. B. Sharpless: Drug Discovery Today Vol. 8 (2003), p.1128.

Google Scholar

[12] K. C. Fylaktakidou, D. J. Hadjipavlou-Litina, K.E. Litinas and D.N. Nicolaides: Current Pharmaceutical Design Vol. 10 (2004), p.3813.

DOI: 10.2174/1381612043382710

Google Scholar

[13] A. Lacy and R. O. Kennedy: Current Pharmaceutical Design 10 (2004), p.3797.

Google Scholar

[14] L. Pochet, R. Frederick and B. Masereel: Current Pharmaceutical Design 10 (2004), p.3781.

Google Scholar