Pattern Transfer of 1μm Sized Microgap and Microbridge Electrode for Application in Biomedical Nano-Diagnostics

Article Preview

Abstract:

We present a new design of biochip for application in clinical diagnostics by using a conventional method of pattern transfer process in microelectronic fabrication. Although there are many advanced techniques available to produce nanostructures such as electron beam lithography (EBL), ion-beam lithography (IBL), focused ion beam milling and nanoimprint lithography, these methods often requires high maintenance costs, time consuming and very complicated compared to conventional photolithography. This conventional technique is still a good choice for a feature size more than 1 micron. In this work, microbridge and microgap design from chrome mask are transferred on silicon wafer to fabricate a biochip. The pattern transfer of the first mask of electrode is presented in this paper to test the repeatability of pattern transfer during photolithography process. Therefore, during the process, the resolution and precise alignment factors are taken into account to prevent circuit and device failure. Post-exposure bake time and development limitations are recorded for both designs.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

533-537

Citation:

Online since:

April 2014

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2014 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] M. Vallet-Regí and D. Arcos, Biomimetic Nanoceramics in Clinical Use: From Materials to Applications. Royal Society of Chemistry, (2008).

DOI: 10.1039/9781847558923-fp011

Google Scholar

[2] M. Debnath, P. S. Bisen, and G. B. K. S. Prasad, Molecular Diagnostics: Promises and Possibilities. Springer, (2010).

Google Scholar

[3] B. D. Malhotra and A. Turner, Advances in Biosensors: Perspectives in Biosensors. Elsevier Science, (2003).

Google Scholar

[4] F. Scheller and F. Schubert, Biosensors. Elsevier Science, (1991).

Google Scholar

[5] Biological and biomedical nanotechnology, vol. 1, no. 3. 2006, p.51.

Google Scholar

[6] D. P. Kern, Nanostructure Fabrication, in Low-Dimensional Electronic Systems SE  - 11, vol. 111, G. Bauer, F. Kuchar, and H. Heinrich, Eds. Springer Berlin Heidelberg, 1992, p.120–133.

Google Scholar

[7] W. E. I. He, K. E. Gonsalves, and C. R. Halberstadt, Micro / Nanomachining and Fabrication of Materials for Biomedical Applications. 2008, p.25–47.

DOI: 10.1002/9780470185834.ch2

Google Scholar

[8] P. Van Zant, Microchip Fabrication: A Practical Guide to Semiconductor Processing. McGraw-Hill, (2000).

Google Scholar

[9] X. Chen, Z. Guo, G. M. Yang, J. Li, M. Q. Li, J. H. Liu, and X. J. Huang, Electrical nanogap devices for biosensing, Materials Today, vol. 13, no. 11, p.28–41.

DOI: 10.1016/s1369-7021(10)70201-7

Google Scholar

[10] R. Doering and Y. Nishi, Handbook of Semiconductor Manufacturing Technology. CRC Press, (2008).

Google Scholar

[11] B. Ziaie, Hard and soft micromachining for BioMEMS: review of techniques and examples of applications in microfluidics and drug delivery, Advanced Drug Delivery Reviews, vol. 56, no. 2, p.145–172, Feb. (2004).

DOI: 10.1016/j.addr.2003.09.001

Google Scholar

[12] A. J. D. Plummer, M. D. Deal, and P. B. G, Silicon VLSI Technology Fundamentals , Practice and Modeling. (2000).

Google Scholar

[13] T. H. S. Dhahi, U. D. A. B. I. N. Hashim, N. M. Ahmed, and A. M. A. T. Taib, A review on the electrochemical sensors and biosensors composed of nanogaps as sensing material, Journal of Optoelectronics and Advanced Materials, vol. 12, no. 9, p.1857–1862, (2010).

Google Scholar

[14] T. S. Dhahi and U. Hashim, Anisotropic Dry Etching ( RIE ) for Micro and Nanogap Fabrication, International Journal of Modern Engineering Research, vol. 2, no. 1, p.9–15.

Google Scholar

[15] K. L. Foo, U. Hashim, H. Prasad, and M. Kashif, Fabrication and characterization of IDE ZnO thin films using sol-gel method for PBS solution measurement, in 2012 10th IEEE International Conference on Semiconductor Electronics, ICSE 2012 - Proceedings, 2012, p.736.

DOI: 10.1109/smelec.2012.6417248

Google Scholar

[16] N. Taib, U. Hashim, A. Saifullah, T. S. Dhahi, and J. K. Setar, Polysilicon Nanogap capacitive biosensors for the pH detection, vol. 1, p.250–252, (2011).

DOI: 10.1109/rsm.2011.6088335

Google Scholar

[17] U. Hashim, K. A. Rahman, and A. R. A. J. Abdullah, Mask design and fabrication of LiSFET for Light Sensor application, 2008 International Conference on Electronic Design, p.1–5, Dec. (2008).

DOI: 10.1109/iced.2008.4786651

Google Scholar

[18] T. S. Dhahi, U. Hashim, N. M. Ahmed, E. Ali, and T. Nazwa, Electrical characterization of in-house fabricated polysilicon micro-gap for yeast concentration measurement, Journal of Engineering and Technology Research, vol. 3, no. August, p.246–254, (2011).

Google Scholar

[19] K. L. Foo, M. Kashif, and U. Hashim, Design and fabrication of nano biologically sensitive field-effect transistor (nano bio-FET) for bio-molecule detection, in AIP Conference Proceedings, 2011, vol. 1341, p.283–288.

DOI: 10.1063/1.3587002

Google Scholar