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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 936Resveratrol Loaded Self-Microemulsifying Drug...

Resveratrol Loaded Self-Microemulsifying Drug Delivery System (SMEDDS): Development and Optimization

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Abstract:

We developed a SMEDDS to enhance the oral delivery of resveratrol by using high performance liquid chromatography, a pseudo ternary phase diagram and a central composite design (CCD). We found that the optimal formulation of 12.69% greoil gtcc, 62.29% Cremophor EL, and 25.02% Labrasol. We characterized the particle size and zeta potential of the final SMEDDS.

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Materials Science and Engineering Technology

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Periodical:

Advanced Materials Research (Volume 936)

Pages:

763-769

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.936.763

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Online since:

June 2014

Authors:

Guo Qing Liu, Hua Feng Zhou, Jing Zhang, Ze Min Yan, Ming Xing Duan, Ying Fang Long, Qiang Xia*

Keywords:

Development, Optimization, Resveratrol, SMEDDS

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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