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Methylthiouracil-Templated Formation of the Fluorescent Silver Nanocluster and its Application to Bioimaging

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Abstract:

Herein, we report a novel approach to Methylthiouracil-templated formation of fluorescent Ag nanoclusters and its application to bioimaging. We used fluorescence assay and TEM to characterize the silver nanocluster. The complex can be directly employed into bioimaging HeLa cells. The cell toxicity (3-[4,5-dimethylthiazolyl-2]-2,5-diphenyltetrazolium bromide, MTT) assay demonstrated that the silver nanocluster has only little affect on the cytotoxicity to the cells, which further proves the applicability of the method in tumor cell imaging. This work successfully develops the capping Methylthiouracil scaffolds of silver nanoclusters.

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Periodical:

Advanced Materials Research (Volume 937)

Pages:

256-259

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.937.256

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Online since:

May 2014

Authors:

Xiao Qing Xu*

Keywords:

Bioimaging Fluorescence, Nanocluster, Silver

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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