Cysteine Conjugated Gold Nanoparticles and their Scavenging Free Radicals Properties

Article Preview

Abstract:

This study deals with cysteine on gold (Au) nanoparticles which prepared by sodium citrate reduction. The effects of cysteine conjugated Au nanoparticles (Cys-c-Au NPs) on the microstructure and properties of the were investigated by Ultraviolet-visible spectroscopy (UV-Vis), Fourier-transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), and free radical scavenging ability. The results of UV-Vis and FTIR show that the cysteine was conjugated on Au NPs surface and the conjugates were found to be stable in water. The Energy-dispersive spectrometer (EDS) result shows the typical pick of the element sulfur (S) on surface of Cys-c-Au NPs. Finally, conjugates exhibited free radical scavenging ability in presence of cysteine.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

112-115

Citation:

Online since:

June 2014

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2014 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] R.C. Bailey, J. -M. Nam, C.A. Mirkin, J.T. Hupp, J. Am. Chem. Soc. 125 (44) (2003) 13541.

Google Scholar

[2] W.J. Parak, D. Gerion, T. Pellegrino, D. Zanchet, C. Micheel S.C. Williams, R. Boudreau, M.A. Le Gros, C.A. Larabell, A.P. Alivisatos, Nanotechnology 14 (2004) 15.

DOI: 10.1088/0957-4484/14/7/201

Google Scholar

[3] M.K. Corbierre, N.S. Cameron, M. Sutton, S.G.J. Mochrie, L.B. Lurio, A. Ruhm, R.B. Lennox, J. Am. Chem. Soc. 123 (42) (2001)10411.

DOI: 10.1021/ja0166287

Google Scholar

[4] T.K. Mandal, M.S. Fleming, D.R. Walt, Nano. Lett. 2 (1) (2002)3.

Google Scholar

[5] J. Shan, M. Nuopponen, H. Jiang, E. Kauppinen, H. Tenhu, Macromolecules 36 (12) (2003) 4526.

Google Scholar

[6] R. Levy, N.T.K. Thanh, R.C. Doty, I. Hussain, R.J. Nichols, D.J. Schiffrin, M. Brust, D.G. Fernig, J. Am. Chem. Soc. 126 (32) (2004)1007.

DOI: 10.1021/ja0487269

Google Scholar

[7] Y.C. Sasaki, K. Yasuda, Y. Suzuki, T. Ishibashi, I. Satoh, Y. Fujiki,S. Ishiwata, Biophys. J. 72 (1997) 1842.

Google Scholar

[8] I. Willner, E. Katz, B. Willner, R. Blonder, V. Heleg-Shabtai, A.F. B¨uckmann, Biosens. Bioelectron. 12 (1997) 337.

DOI: 10.1016/s0956-5663(96)00065-6

Google Scholar

[9] J.L. Burt, C. Gutierrez-Wing, M. Miki-Yoshida, M. Jose-Yacaman, Langmuir 20 (26) (2004) 11778.

Google Scholar

[10] Mucic, R.C., Storhoff, J.J., Mirkin, C.A., Letsinger, R.L. J. Am. Chem. Soc. 1998, 120, 12674-12675D. Neher, Macromol. Rapid Commun., 22, (2001) 17.

DOI: 10.1021/ja982721s

Google Scholar

[11] N. Chanda, R. Shukla, A. Zambre, S. Mekapothula, R.R. Kulkarni, K. Katti et al. Pharm Res, 28 (2011) 279.

Google Scholar

[12] P.S. Ghosh, C.K. Kim, G. Han, N.S. Forbes, V.M. Rotello, ACS Nano, 2 (2008), 2213.

Google Scholar