Efficient Synthesis 2,3-Dihydroquinazolin-4(1H)-Ones Using Coconut Shell Char Sulfonic Acid as a Reusable Catalyst in Ethanol

Xuan Yan Liu; Zhi Gao Yang

doi:10.4028/www.scientific.net/AMR.989-994.83

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 989-994Efficient Synthesis...

Efficient Synthesis 2,3-Dihydroquinazolin-4(1H)-Ones Using Coconut Shell Char Sulfonic Acid as a Reusable Catalyst in Ethanol

Abstract:

3,4-Dihydropyrimidin-2(1H)-ones derivatives were synthesized in moderate to high yields in one-pot three component reaction from the corresponding aldehydes, 1,3-dicarbonyl compounds and urea, Coconut shell char sulfonic acid (CSCSA) used as a reusable, and efficient catalyst. Compared to the classical acid catalyst, This new protocol for the Biginelli reaction includes the following important features: excellent yields, non-toxic, inexpensive and easily available reagent.

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Advanced Materials Research (Volumes 989-994)

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83-86

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.989-994.83

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Online since:

July 2014

Authors:

Xuan Yan Liu*, Zhi Gao Yang

Keywords:

Biginelli Reaction, CSCSA, Di-Hydropyrimidin, Heterogeneous Catalysts

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