Inhibition of Tumor Cell Proliferation In Vitro by Benzamide Derivatives

Yan Ling Wu; Li Wen Shen; Yan Ping Ding; Yoshimasa Tanaka; Wen Zhang

doi:10.4028/www.scientific.net/AMR.997.225

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Inhibition of Tumor Cell Proliferation In Vitro by Benzamide Derivatives
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 997Inhibition of Tumor Cell Proliferation In Vitro by...

Inhibition of Tumor Cell Proliferation In Vitro by Benzamide Derivatives

Abstract:

Benzamide derivatives have been shown to have antitumor activity in various tumor cell lines in vitro as well as in vivo. In this study, we examined the anti-proliferative effect of four benzamide derivativeson Hela, H7402, and SK-RC-42 tumor cell lines in vitro by means of Real-Time cell assay (RTCA), and found that four benzamide derivatives suppressed proliferation of tumor cells in a time-and dose-dependent manner. The anti-proliferative activity of benzamide derivatives demonstrated that theycould be promising lead compounds for developing therapeutic agents for malignant tumors.

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Periodical:

Advanced Materials Research (Volume 997)

Pages:

225-228

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.997.225

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Online since:

August 2014

Authors:

Yan Ling Wu*, Li Wen Shen, Yan Ping Ding, Yoshimasa Tanaka, Wen Zhang

Keywords:

Anti-Proliferative Activity, Benzamide Derivatives, Real-Time Cell Assay, Tumor Cells

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