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HomeDefect and Diffusion ForumDefect and Diffusion Forum Vols. 334-335Optical Chemical Nanosensors in Clinical...

Optical Chemical Nanosensors in Clinical Applications

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Abstract:

Because of their size and versatile chemistry, nanomaterials represent today powerful tools for (bio) sensing applications. Various types of nanomaterials have proven to be practical, not only for the determination of clinically relevant parameters, but also for diagnostics, drug delivery and treatment of diseases (e.g. cancer). In this short review, types of nanomaterials used in medical applications are briefly described along with some of their applications where the nanomaterials optical properties can be exploited. The question of the toxicity of nanomaterials and the issue of future trends are also raised.

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Diffusion in Solids and Liquids VIII

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Defect and Diffusion Forum (Volumes 334-335)

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387-396

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https://doi.org/10.4028/www.scientific.net/DDF.334-335.387

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February 2013

Authors:

Matejka Turel, Tinkara Mastnak, Aleksandra Lobnik

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Clinical Applications, Nanomaterial, Optical Sensing

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[1] T. Vo-Dinh, Optical Nanosensors for Detecting Proteins and Biomarkers in Individual Living Cells: in Protein Nanotechnology, Vol. 300, p.383, ed.: T. Vo-Dinh, Humana Press Inc., Totowa, NJ (2005).

DOI: 10.1385/1-59259-858-7:383

[2] A.P. Demchenko, Sensing Inside Living Cells and Tissues, chapter 11 in: Introduction to Fluorescence Sensing (Springer, 1st ed. 2009), p.455.

[3] T. Vo-Dinh and Y. Zhang: WIREs Nanomedicine and Nanobiotechnology, 3-1 (2010) 79.

[4] H. Maeda, J. Wu, T. Sawa, Y. Matsumura, K. Hori: J. Control. Release 65 (2000) 271.

[5] J.R. McCarthy, R. Weissleder: Advanced Drug Delivery Reviews 60 (2008) 1241.

[6] J.B. Haun, N.K. Devaraj, S.A. Hilderbrand, H. Lee, R. Weissleder: Nat. Nanotechnol. 5 (2010) 660.

[7] C. Tassa; J.L. Duffner, T.A. Lewis: Bioconjugate Chem., 21 (2009) 14.

[8] S. Hong, P. Leroueil, I. Majoros, B. Orr, J. Baker, M. Holl: Chem. Biol. 14 (2007) 107–1.

[9] S.Y. Shaw, E.C. Westly, M.J. Pittet, A. Subramanian, S.L. Schreiber, R. Weissleder: Proc. Natl Acad Sci USA 105 (2008) 7387.

DOI: 10.1073/pnas.0802878105

[10] J.H. Lee, Y.W. Jun, S.I. Yeon, J.S. Shin, J. Cheon: Angew Chem Int Ed 45 (2006) 8160.

[11] T. Atanasijevic, M. Shusteff, P. Fam, A. Jasanoff: Proc Natl Acad Sci USA 103 (2006) 14707.

DOI: 10.1073/pnas.0606749103

[12] J.F. Lutz, S. Stiller, A. Hoth, L. Kaufner, U. Pison, R. Cartier: Biomacromolecules 7 (2006) 3132.

DOI: 10.1021/bm0607527

[13] M. Ferrari: Nat Rev Cancer 5 (2005) 161.

[14] A.K. Iyer, G. Khaled, J. Fang, H. Maeda: Drug Discov Today 11 (2006) 812.

[15] P. Ghosh, G. Han, M. De, C.K. Kim, V.M. Rotello: Adv Drug Deliv Rev 60 (2008) 1307.

[16] P. Broz (ed. ): Polymer-based Nanostructures, Medical Application (RSC, 2010).

[17] Y.E. Koo Lee, E.E. Ulbrich, G. Kim, H. Hah, C. Strollo, W. Fan, R. Gurjar, S.M. Koo and R. Kopelman: Anal Chem 82 (2010) 8446.

DOI: 10.1021/ac1015358

[18] X. He, J. Gao, S. S. Gambhir Z. Cheng: Trends Mol Med 16-12 (2010) 574.

[19] J. Napp, T. Behnke, L. Fischer, C. Würth, M. Wottawa, D.M. Katschinski, F. Alves, U. Resch-Genger, M. Schäferling: Anal Chem 83 (2011) 9039.

DOI: 10.1021/ac201870b

[20] S.E.D. Webb, S.R. Needham, S.K. Roberts, M.L. Martin-Fernandez: Opt Lett 31 (2006) 2157.

[21] D.S. Grubisha, R.J. Lipert, H.Y. Park, J. Driskell, M.D. Porter: Anal Chem 75 (2003) 5936.

[22] J. Kneipp, H. Kneipp, B. Wittig, K. Kneipp: Nanomedicine: Nanotechnology, Biology, and Medicine 6 (2010) 214.

DOI: 10.1016/j.nano.2009.07.009

[23] A.J. Haes, R.P. Van Duyne: Proceedings of the SPIE, Vol. 5221 Plasmonics: Metallic Nanostructures and Their Optical Properties (2003) 47.

[24] Q. Xiao, L. Zhang, C. Lu: Sensor Actuat B-Chem 166-167 (2012) 650.

[25] T.Y. Ohulchanskyy, I. Roy, K. -T. Yong, H.E. Pudavar, P.N. Prasad: WIREs: Nanomedicine and Nanobiotechnology 2-2 (2010) 162.

[26] P.V. Baptista, M. Koziol-Montewka, J. Paluch-Oles, G. Doria, R. Franco: Clin Chem 52 (2006) 1433.

DOI: 10.1373/clinchem.2005.065391

[27] X. Huang, P.K. Jain, I.H. El-Sayed, M.A. El-Sayed: Nanomedicine 2(5) (2007) 681.

[28] C.C. Huang, C.K. Chiang, Z.H. Lin, K.H. Lee, H.T. Chang: Anal Chem 80-5 (2008) 1497.

[29] T. Niidome, Y. Akiyama, K. Shimoda, T. Kawano, T. Mori, Y. Katayama, Y. Niidome: Small 4 (2008) 1001.

DOI: 10.1002/smll.200700438

[30] X. Huang, M.A. El-Sayed: Journal of Advanced Research 1 (2010) 13.

[31] L.R. Hirsch, R.J. Stafford, J.A. Bankson, S.R. Sershen, B. Rivera, R.E. Price, J.D. Hazle, N.J. Halas, J.L. West: Proc Natl Acad Sci USA 100-23 (2003) 13549.

DOI: 10.1073/pnas.2232479100

[32] M.E. Wieder, D.C. Hone, M.J. Cook, M.M. Handsley, J. Gavrilovic, D.A. Russell: Photochem Photobiol Sci 5 (2006) 727.

DOI: 10.1039/b602830f

[33] A. Ambrosi, F. Airò, A. Merkoçi: Anal Chem 82 (2010) 1151.

[34] S. Kim, R.N. Zare: Methods Enzymol 472 (2010) 119.

[35] X. Huang, I.H. El-Sayed, W. Qian, M.A. El-Sayed: J Am Chem Soc 128-6 (2006) 2115.

[36] K. Sokolov, M. Follen, J. Aaron, I. Pavlova, A. Malpica, R. Lotan, R. Richards-Kortum.: Cancer Res 63-9 (2003) (1999).

[37] K. Sokolov, J. Aaron, B. Hsu, D. Nida, A. Gillenwater, M. Follen, C. MacAulay, K. Adler-Storthz, B. Korgel, M. Descour, R. Pasqualini, W. Arap, W. Lam, R. Richards-Kortum: Technol Cancer Res Treat 2-6 (2003) 491.

DOI: 10.1177/153303460300200602

[38] C. Loo, A. Lin, L. Hirsch, M.H. Lee, J. Barton, N. Halas, J. West, R. Drezek: Technol Cancer Res Treat 3-1 (2004) 33.

DOI: 10.1177/153303460400300104

[39] I.H. El-Sayed, X. Huang, M.A. El-Sayed: Nano Lett 5-5 (2005) 829.

[40] Y. Xia, N.J. Halas: MRS Bull 30-5 (2005) 338.

[41] Y.Y. Yu, S.S. Chang, C.L. Lee, C.R.C. Wang: J Phys Chem B 101-34 (1997) 6661.

[42] B. Nikoobakht, M.A. El-Sayed: Chem Mater 15-10 (2003) (1957).

[43] C.J. Murphy, T.K. Sau, A.M. Gole, C.J. Orendorff, J. Gao, L. Gou, S.E. Hunyadi, T. Li: J Phys Chem B 109-29 (2005) 13857.

DOI: 10.1021/jp0516846

[44] S.J. Oldenburg, R.D. Averitt, S.L. Westcott, N.J. Halas: Chem Phys Lett 288-2–4 (1998) 243.

[45] Y. Sun, B.T. Mayers, Y. Xia: Nano Lett 2-5 (2002) 481.

[46] J. Chen, D. Wang, J. Xi, L. Au, A. Siekkinen, A. Warsen, Z.Y. Li, H. Zhang, Y. Xia, X. Li: Nano Lett 7-5 (2007) 1318.

DOI: 10.1021/nl070345g

[47] E.E. Connor, J. Mwamuka, A. Gole, C.J. Murphy, M.D. Wyatt: Small 1 (2005) 325.

[48] S. Ray, P.J. Reddy, S. Choudhary, D. Raghu, S. Srivastava: J Proteomics 74 (2011) 2660.

[49] U. Resch-Genger, M. Grabolle, S. Cavaliere-Jaricot, R. Nitschke, T. Nann: Nat Methods 5 (2008) 763.

DOI: 10.1038/nmeth.1248

[50] K.J. Kewal: Clin Chim Acta 358 (2005) 37.

[51] H.M. Azzazy, M.M. Mansour, S.C. Kazmierczak: Clin Biochem 40 (2007) 917.

[52] Z. Deng, Y. Zhang, J. Yue, F. Tang and Q. Wei: J Phys Chem B 111 (2007) 12024.

[53] K. Joo, A. Tai and P. Wang in: Imaging and tracking of viruses using quantum dots, edited by C.S.S.R. Kumar, Nanomaterials for the Life Sciences Vol. 6: Semiconductor Nanomaterials, chapter 6, Wiley-VCH Verlag GmbH & Co. KGaA, (2010).

[54] X. Wu, H. Liu, J. Liu, K.N. Haley, J.A. Treadway, J.P. Larson, N. Ge, F. Peale, M.P. Bruchez: Nat Biotechnol 21 (2003) 41.

DOI: 10.1038/nbt764

[55] A.M. Smith, S. Dave, S. Nie, L. True, X. Gao: Expert Rev Mol Diagn 6-2 (2006) 231–44.

[56] N. Bartneva and I. Vorobjev, in: Quantum Dots in microscopy and cytometry, ed. by A. Méndez-Villas and J. Díaz, Microscopy: Science, Technology, Applications and Educations, Fromatex (2010).

[57] A.J. Tavares, L. Chong, E. Petryayeva, W.R. Algar, U.J. Krull: Anal Bioanal Chem 399 (2011) 2331.

[58] Y. Xing, J. Rao: Cancer Biomark 4 (2008) 307.

[59] K.J. Cash, H.A. Clark: Trends Mol Med 16-12 (2010) 584.

[60] P. Wu, Y. He, H.F. Wang, X.P. Yan: Anal Chem 82 (2010) 1427.

[61] C.P. Soman, T.D. Giorgio: Langmuir 24 (2008) 4399.

[62] M.A. Hahn, P.C. Keng, T.D. Krauss: Anal Chem 80 (2008) 864.

[63] H. Mukundan, H. Xe, D. Price, J.Z. Kubicek-Sutherland, W.K. Grace, A.S. Anderson, J.S. Martinez, N. Hartman, B.I. Swanson: Anal Chem 82 (2010) 136.

DOI: 10.1021/ac901497g

[64] J. Dobson: Drug Dev Res 67 (2006) 55.

[65] I.I. Slowing, B.G. Trewyn, S. Giri and V.S. -Y. Lin: Adv Funct Mater 17 (2007) 1225.

[66] R. Hergt, S. Dutz, R. Müller, M. Zeisberger: J Phys-Condens Mat 18 (2006) S2919.

[67] P. Gould: Nano Today 1-4 (2006) 34.

[68] J. Grimm, J.M. Perez, L. Josephson, R. Weissleder: Cancer Res 64 (2004) 639.

[69] E.Q. Song, J. Hu, C.Y. Wen, Z.Q. Tian, X. Yu, Z.L. Zhang, Y.B. Shi, D. -W, Pang: ACSNano, 5-2 (2011) 761.

[70] B. Zhang, B. Chen, Y. Wang, F. Guo, Z. Li, D. Shi: J Colloid Interf Sci 353 (2011) 426.

[71] Y. Ge,Y. Zhang, S. He, F. Nie, G. Teng, N. Gu: Nanoscale Res Lett 4-4 (2009) 287–95.

[72] R. Wilson, D.G. Spiller, I.A. Prior, K.J. Veltkamp, A. Hutchinson: ACSNano 1-5 (2007) 487.

[73] A. Lapresta Fernandez, T. Doussineau, A.J. Moro, S. Dutz, F. Steiniger, G.J. Mohr: Anal Chim Acta 707 (2011) 164.

DOI: 10.1016/j.aca.2011.09.008

[74] Y. Zhang, S.W.Y. Gong, L. Jin, S.M. Li, Z.P. Chen, M. Ma, N. Gu: Chin Chem Lett 20 (2009) 969.

[75] V. Malinova And W. Meier: Polymer Materials for Biomedical Applications, edited by Brož, Polymer-based nanostructures, Medical Applications, chapter 1, RSC publishing (2010).

DOI: 10.1039/9781847559968-00003

[76] N. Sato, T. Okada, H. Horiuchi, N. Murakami, J. Takakashi, M. Nawata, H. Ota, K. Nozaki, K. Takaoka: Nat Biotechnol 19 (2001) 332.

DOI: 10.1038/86715

[77] U. Izhar, H. Schwalb, J.B. Borman, G.R. Hellener, A. Hotoveli-Salomon, G. Marom, T. Stern, D. Cohn: J Surg Res 95 (2001) 152.

DOI: 10.1006/jsre.2000.6042

[78] K.E. Uhrich, S.M. Cannizzaro, R.S. Langer, K.M. Shakesheff: Chem Rev 99 (1999) 3181.

[79] M.N.V. Ravikumar, N. Kumar: Drug Dev Ind Pharm 27 (2001) 1.

[80] K.H. Lam, A.J. Nijenhuis, H. Bartels, A.R. Postema, M.F. Jonkman, A.J. Pennings, P. Nieuwenhuis: J Appl Biomater 6 (1995) 191.

DOI: 10.1002/jab.770060308

[81] J.W. Leenslag, A.J. Pennings, R.R. Bos, F.R. Rozema, G. Boering: Biomaterials 8 (1987) 70.

[82] C.H. Jurgens, H.R. Kricheldorf, I. Kreiser-Saunders, Development of a biodegradable wound covering and first clinical results in G.H.I.M. Walenkamp Biomaterials in Surgery, ed.; G. Thieme-Verlag: New York (1998) p.112–20.

[83] F. Shi, R.A. Gross, D.R. Rutherford: Macromolecules 29 (1996) 10.

[84] F. Shi, R. Ashby, R.A. Gross: Macromolecules 29 (1996) 7753.

[85] S. Takada, Y. Uda, H. Toguchi, Y. Ogawa: J Pharm Sci Technol 49 (1995) 180.

[86] C. Damgé, C. Michel, M. Aprahamian, P. Couvreur, J.P. Devissaguet: J Control Release, 13 (1990) 233.

DOI: 10.1016/0168-3659(90)90013-j

[87] W. Tan, K. Wang, X. He, X.J. Zhao, T. Drake, L. Wang, R.P. Bagwe: Med Res Rev 24 (2004) 621.

[88] H.K. Kim, S. -J. Kang, S. -K. Choi, Y. -H. Min, C. -S. Yoon: Chem Mater 11 (1999) 779.

[89] W. Liana, S.A. Litherlandb, H. Badranea, W. Tanc, D. Wud, H.V. Bakera, P.A. Guliga, D.V. Lime, S. Jin: Anal Biochem 334 (2004) 135.

[90] J. E. Smith, L. Wang, W. Tan: Trends Anal Chem 25 (2006) 848.

[91] L. Wang, C. Yang, W. Tan: Nano Lett 5 (2005) 37.

[92] T. Deng, J.S. Li, J.H. Jiang, G.L. Shen, R.Q. Yu: Adv Funct Mater 16 (2006) 2147.

[93] M. Tan, G. Wang, X. Hai, Z. Ye, J, Yuan: J Mater Chem 14 (2004) 2896.

[94] X. He, J. Duan, K. Wang, W. Tan, X. Lin, C. He: J Nanosci Nanotechnol 4 (2004) 585.

[95] R. P. Bagwe, C. Yang, L.R. Hilliard, W. Tan: Langmuir 20 (2004) 8336.

[96] G. Yao, L. Wang, Y. Wu, J. Smith, J. Xu, W. Zhao, E. Lee, W. Tan: Anal Bioanal Chem 385 (2006) 518.

[97] R. P. Bagwe, L.R. Hilliard, W. Tan: Langmuir 22 (2006) 4357.

[98] X. Zhao, R.P. Bagwe, W. Tan: Adv Mater 16 (2004) 173.

[99] L. Wang, K. Wang, S. Santra, X. Zhao, L.R. Hilliard: Anal Chem 78 (2006) 646A.

[100] F. Wang, D.K. Chatterjee, Z. Li, Y. Zhang, X. Fan, M. Wang: Nanotechnology 17 (2006) 5786.

[101] J. Shen, L. Zhao, G. Han: Adv Drug Deliver Rev (2012) doi: 10. 1016/j. addr. 2012. 05. 007.

[102] Z. Ma, D. Dosev, M. Nichkova, R.K. Dumas, S.J. Gee, B.D. Hammock, K. Liu, I.M. Kennedy: Anal Chem 77 (2005) 6864.

[103] R.S. Niedbala, H. Feindt, K. Kardos, T. Vail, J. Burton, B. Bielska, S. Li, D. Milunic, P. Bourdelle, R. Vallejo: Anal Biochem 293 (2001) 22.

DOI: 10.1006/abio.2001.5105

[104] V. Väisänen, H. Härmä, H. Lilja, A. Bjartell: Luminescence 15 (2000) 389.

[105] H. Hu, L.Q. Xiong, J. Zhou, F.Y. Li , T.Y. Cao, C.H. Huang: Chem Eur J 15 (2009) 3577.

[106] S. Gai, P. Yang, C. Li, W. Wang, Y. Dai, Niu N, J. Lin: Adv Funct Mater 20 (2010) 1166.

[107] E. Beaurepaire, V. Buissette, M. -P. Sauviat, D. Giaume, K. Lahlil, A. Mercuri, D. Casanova, A. Huignard, J. -L. Martin, T. Gacoin, J. -P. Boilot, A. Alexandrou: Nano Lett 4 (2004) (2079).

DOI: 10.1021/nl049105g

[108] Y. Chen, Y.M. Chi, H.M. Wen, Z.H. Lu: Anal. Chem. 79 (2007) 960.

[109] F. Gao, F. Luo, X. Chen, W. Yao, J. Yin, Z. Yao, L. Wang: Talanta 80 (2009) 202.

[110] E. Monson, M. Brasuel, M.A. Philbert, R. Kopelman: PEBBLE Nanosensors for in Vitro Bioanalysis: in Biomedical Photonics Handbook, ed.: T. Vo-Dinh, CRC Press, Florida (2003).

DOI: 10.1201/9780203008997.ch59

[111] J. Sumner, J. Aylott, E. Monson, R. Kopelman: Analyst 127 (2002) 11.

[112] M. Brasuel, R. Kopelman, T.J. Miller, R. Tjalkens, M.A. Philbert: Anal Chem 73 (2001) 2221.

[113] Y. -E. L. Koo, Y. Cao, R. Kopelman: Anal Chem 76 (2004) 2498.

[114] S.M. Buck, H. Xu, M. Brasuel, M.A. Philbert, R. Kopelman: Talanta 63 (2004) 41.

[115] E.J. Park, M. Brasuel, C. Behrend, M.A. Philbert, R. Kopelman: Anal Chem 75 (2003) 3784.

[116] H.A. Clark, M. Hoyer, S. Parus, M.A. Philbert, M. Kopelman: Microchim Acta 131 (1999) 121.

[117] H.A. Clark, S.L.R. Barker, M. Brasuel, M.T. Miller, E. Monson, S. Parus, Z.Y. Shi, A. Song, B. Thorsrud, R. Kopelman, A. Ade, W. Meixner, B. Athey, M. Hoyer, D. Hill, R. Lightle, M.A. Philbert: Sens Actuators B-Chem. 51 (1998) 12.

DOI: 10.1016/s0925-4005(98)00212-3

[118] H.A. Clark, R. Kopelman, R. Tjalkens, M.A. Philbert: Anal Chem 71 (1999) 4837.

[119] M. Brasuel, R. Kopelman, I. Kasman, T.J. Miller, M.A. Philbert: Proc. IEEE 1 (2002) 288.

[120] M.G. Brasuel, T.J. Miller, R. Kopelman, M.A. Philbert: Analyst 128 (2003) 1262.

[121] H. Xu, J.W. Aylott, R. Kopelman, T.J. Miller, M.A. Philbert: Anal Chem 73 (2001) 4124.

[122] C.M. Janczak in Hybrid nanoparticles for enhanced sensitivity in biological labeling and biomolecular sensing, Dissertation, University of Arizona, (2011).

[123] P. Tallury, A. Malhorta, L.M. Byrne, S. Santra: Adv Drug Deliver Rev 62 (2010) 424.

[124] L. Wang, W.J. Zhao, M.B. O'Donoghue, W.H. Tan: Bioconjug Chem 18 (2007) 297.

[125] K.J. Kewal: Clin Chem 53-11 (2007) (2002).

[126] J. Xie, S. Lee, X. Chen: Adv Drug Deliver Rev 62 (2010) 1064.

[127] T.F. Massoud, S.S. Gambhir: Genes Dev 17 (2003) 545.

[128] P. Rai, S. Mallidi, X. Zheng, R. Rahmanzadeh, Y. Mir, S. Elrington, A. Khurshid and T. Hasan: Adv Drug Deliver Rev 62 (2010) 1094.

DOI: 10.1016/j.addr.2010.09.002

[129] L. Zhang, F.X. Gu, J.M. Chan, A.Z. Wang, R.S. Langer, O.C. Farokhzad: J Clin Pharm Ther 83-5 (2008) 761.

[130] D. Bechet, P. Couleaud, C. Frochot, M. -L. Virio, F. Guillemin, M. Barberi-Heyob: Trends Biotechnol 26-11 (2008) 612.

DOI: 10.1016/j.tibtech.2008.07.007

[131] J. Ji, N. Rosenzweig, C. Griffin, Z. Rosenzweig: Anal Chem 72 (2000) 3497.

[132] H. Clark, M. Hoyer, M. Philbert, R. Kopelman: Anal Chem 71 (1999), 4831.

[133] A. Lapresta-Fernandez, P.J. Cywinski, A.J. Moro, G.J. Mohr: Anal Bioanal Chem 395 (2009) 1821.

[134] R.L. Phillips, O.R. Miranda, C.C. You, V.M. Rotello, U.H. Bunz: Angew Chem Int. Ed Engl 47 (2008) 2590.

[135] D. Qin, X. He, K. Wang, X.J. Zhao, W. Tan, J. Chen: J Biomed Biotechnol (2007) 1.

[136] A.B. Descalzo, M.D. Marcos, R. Martinez-Manez, J. Soto, D. Beltran, P. Amoros: J Mater Chem 15 (2005) 2721.

[137] V.S.Y. Lin, C. -Y. Lai, J. Huang, S. -A. Song, S. Xu: J Am Chem Soc 123 (2001) 11510.

[138] R. Weissleder: Science 312 (2006) 1168.

[139] J.V. Frangioni: Curr Opin Chem Biol 7 (2003) 626.

[140] Y. Koyama, Talanov V.S., M. Bernardo, Y. Hama, C.A. Regino, M.W. Brechbiel, P.L. Choyke, H. Kobayashi: J Magn Reson Imaging 25-4 (2007), 866.

DOI: 10.1002/jmri.20852

[141] L. Brannon-Peppas, J.O. Blanchette: Adv Drug Deliv Rev 56 (2004) 1649.

[142] E.S. Kawasaki, A. Player: Nanomedicine 1 (2005) 101.

[143] J.L. Vivero-Escoto, I.I. Slowing, B.G. Trewyn, V.S. -Y. Lin: Small 6-18 (2010) (1952).

[144] D.A. Groneberg, M. Giersig, T. Welte, U. Pison: Curr Drug Targets, 7-6 (2006) 643.

[145] C. -Y. Lai , B. G. Trewyn , D. M. Jeftinija , K. Jeftinija , S. Xu , S. Jeftinija , V. S. Y. Lin , J. Am. Chem. Soc. 125 (2003) 44514459.

DOI: 10.1021/ja028650l

[146] J.L. Vivero-Escoto, I.I. Slowing, C.W. Wu, V.S.Y. Lin: J Am Chem Soc 131 (2009) 3462.

[147] J.E. Lee, N. Lee, H. Kim, J. Kim, S.H. Choi, J.H. Kim, T. Kim, I.C. Song, S.P. Park, W.K. Moon, T. Hyeon: J Am Chem Soc 132 (2010) 552.

[148] D.R. Radu, C. -Y. Lai, K. Jeftinija, E.W. Rowe, S. Jeftinija, V.S.Y. Lin: J Am Chem Soc 126 (2004) 13216.

DOI: 10.1021/ja046275m

[149] Y. Zhao, B.G. Trewyn, I.I. Slowing, V.S.Y. Lin: J Am Chem Soc. 131 (2009) 8398.

[150] D.R. Radu, C.Y. Lai, J.W. Wiench, M. Pruski, V.S.Y. Lin: J Am Chem Soc 126 (2004) 1640.

[151] Z.H. Xu, C.X. Li, P.G. Ma, Z.Y. Hou, D.M. Yang, X.J. Kang: Nanoscale 3 (2011) 661.

[152] Z. Xu, P.G. Ma, C.X. Li, Z.Y. Hou, X.F. Zhai, S.S. Huang, J. Lin: Biomaterials 32 (2011) 4161.

[153] S. Gai, P. Yang , C. Li, W. Wang, Y. Dai, N. Niu, J. Lin: Adv Funct Mater 20 (2010) 1166.

[154] S.R. Sershen, S.L. Westcott, N.J. Halas, J.L. West: J Biomed Mater Res 51 (2000) 293.

[155] J.P. Celli, B.Q. Spring, I. Rizvi, C.L. Evans, K.S. Samkoe, S. Verma, B.W. Pogue, T. Hasan: Chem. Rev. 110 (2010) 2795.

DOI: 10.1021/cr900300p

[156] C. Wang, H.Q. Tao, L. Cheng, Z. Liu: Biomaterials 32 (2011) 6145.

[157] W. Tang, H. Xu, R. Kopelman, M.A. Philbert: Photochem Photobiol 81 (2005) 242.

[158] T.Y. Ohulchanskyy, I. Roy, L.N. Goswami, Y.H. Chen, E.J. Bergey, R.K. Pandey, A.R. Oseroff, P.N. Prasad: Nano Lett 7 (2007) 2835.

DOI: 10.1021/nl0714637

[159] S. Kim, T.Y. Ohulchanskyy, H.E. Pudavar, R.K. Pandey, P.N. Prasad: J Am Chem Soc 129 (2007) 2669.

[160] L. Cheng, K. Yang, Y.G. Li, J.H. Chen, C. Wang, M.W. Shao, S.T. Lee, Z. Liu: Angew Chem Int Ed 50 (2011) 7385.

[161] B.A. Dong, S. Xu, J.A. Sun, S. Bi, D. Li, X. Bai, Y. Wang, L.P. Wang, H.W. Song: J Mater Chem 21 (2011) 6193.

[162] A.M. Gobin, M.H. Lee, N.J. Halas, W.D. James, R.A. Drezek, J. L West: Nano Lett 7 (2007) (1929).

[163] N. Lewinski, V. Colvin, R. Drezek: Small 4-1 (2008) 26.

[164] H. Mattoussi, G. Palui, H.B. Na: Adv Drug Deliver Rev 64 (2012) 138–66.

[165] P.C. Ray, H. Yu, P.P. Fu: J Environ Sci Health C 27-1 (2009) 1.