Biocompatibility of Hydrophilicity Improved Apatite Cement

Abstract:

Hydrophilicity of apatite cement was increased after O₃ gas treatment on apatite cement (AC) powder. It results on the improvement of the handling and mechanical properties of set AC. Behavior of osteoblastic cells to O₃-treated set AC was evaluated including initial cell attachment, morphology of the attached cells and proliferation using rat bone marrow cell (RBM). Cells’ response to the set AC was the same regardless of O₃ treatment. The cells well attached and spread with filopodial extensions even over the O₃-treated set AC specimens. The rates of cell proliferation on set AC were also the same regardless of O₃ treatment. The result indicated O₃ treatment of AC powder would not affect to the osteoblast cell response of set AC.

• Periodical: Journal of Biomimetics, Biomaterials and Biomedical Engineering (Volume 43)
• Pages: 124-129
• DOI: https://doi.org/10.4028/www.scientific.net/JBBBE.43.124
• Online since: November 2019
• Authors: Ira Artilia*, Kanji Tsuru, Kunio Ishikawa
• Keywords: Apatite Cement, Biocompatibility, Surface Modification

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