Preservation of Bone Tissue Quality during the Usage of Synthetic Bioactive Calcium Phosphate Mineral Coating for Prevention of Metallic Construction Migration

Abstract:

This work is devoted to studying the reaction of bone tissue to installed titanium implants, which are bioinert in comparison with other metals used in traumatological and orthopedic practice, but which have a negative effect on bone tissue in the implant-to-bone area. In order to increase the affinity of the implant surface with bone tissue, it was proposed to use synthetic bioactive calcium phosphate mineral coating by applying it on titanium implants, which ultimately will make it possible to maintain the quality of the bone tissue around the implant after osteosynthesis or prosthetics. During the comparative research an in vivo experiment was conducted in which quality change of peri-implant zone of bone tissue when using titanium implants with synthetic bioactive calcium phosphate mineral coating and titanium implants without bioactive coating was analyzed. To analyze the results of the study, we used the X-ray computed tomography method, for a detailed assessment of the X-ray density and bone mineral density of the peri-implant zone. According to the results of the experiment, it was concluded that the reaction of bone tissue to synthetic bioactive calcium phosphate mineral coating of titanium implants was reduced, what ensures the preservation of bone tissue quality in the postoperative period at a high level.

• Periodical: Journal of Biomimetics, Biomaterials and Biomedical Engineering (Volume 46)
• Pages: 67-74
• DOI: https://doi.org/10.4028/www.scientific.net/JBBBE.46.67
• Online since: June 2020
• Authors: Alexander Markov, Andrey Ponomarev, Mikhail Zavatskij, Ksenya Stepanova, Sergej Krylov, Mikhail Naumov
• Keywords: Bone Tissue Reparative Regeneration, Computer X-Ray Microtomography, Synthetic Bioactive Calcium Phosphate Mineral Coating

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