Journal of Biomimetics, Biomaterials and Biomedical Engineering Vol. 53

Abstract: Biomedical technologies (BMT) is a complex process aimed at developing new biological objects and products from them that can have a preventive, diagnostic, or therapeutic effect when used in medical practice. The article describes the development of biomedical technologies, the problems of the development of biomedical technologies, and also describes possible ways to solve them.

Abstract: In modern medicine, biotechnological products and systems are used and widely studied, in which various elements and parts interact with biological fluids, soft and hard muscle tissues. This mainly concerns products used in cardiovascular surgery, orthopaedic surgery, dentistry and reconstructive surgery, as well as in ophthalmology. The article studies scientific approaches to the creation of biocompatible implant materials, considers their types, defines the basic requirements for biocompatible materials.

Abstract: Hallux valgus (HV) violates the musculoskeletal function of the lower limb, and also affect the x-ray anatomical parameters of the foot. There is the study of the most important correlations between age, morphological and functional changes of the forefoot play a big role in the choice of treatment tactics for this pathology. The aim was to analyze the age, functional and radiological results of surgical treatment of Hallux valgus deformity of the first toe using the methods saving the metatarsophalangeal joint. 126 patients had Hallux valgus deformity of the first toe of I, II, III degree. They were examined before surgery, then 3, 6 and 12 months after operation. 126 patients were operated according to the method of Scarf, Austin, Bosch-Magnan osteotomy. X-ray results were assessed by the Hallux valgus angle (HVA), the intermetatarsal angle (IMA), the distal metatarsal articular angle (DMMA) before and after the operations. AOFAS rating scale (Kitaoka) and biomechanical (stabilometric) study were used for the functional assessment of the surgical treatment results. The IMA correction angle after operation increases with the patient's age. HVA becomes the most deformed angle in the pathology of Hallux valgus with increasing age before osteotomy. The best functional result according to the AOFAS scale was obtained with the greatest correction of the IMA angle after osteotomy. The functional index of the foot decreased with increasing age after osteotomies.

Abstract: Decades ago, implants appeared that were used to restore lost teeth. Improvement work continues to this day. Specialists are interested in increase in the reliability and strength, as well as in the high quality of fusion of implants with living tissue. The article studies scientific approaches to the creation of biocompatible dental materials, considers their types, defines the basic requirements for biocompatible dental materials.

Abstract: The article summarizes information about the head ganglia (the sympathetic ganglia and in the sensory cranial nerves). Gives а brief historical background on the history issue and relevance of the topic. Characterized by each node with its topography and lesion clinic. The described process of treatment, and prospects for new therapies. Raised the issue of the significance of the defeat ganglia, namely, the suffering of the sick and forced treatment costs (due to the complex differential diagnosis). In a biological sense, pain first appears in chordates and during evolution, as well as transformations of the brain and spinal cord, it acquires new types, localization and significance for the performance of a living organism. And facial pain, being a nosology with a multidisciplinary approach in diagnosis and treatment, demonstrates both its complexity and importance in human life.

Abstract: Degenerative pathology of the musculoskeletal system is one of the main reasons for decreased mobility in patients of the older age group. Increasing the life expectancy leads to predominance non-epidemic pathology in all developed countries. Therefore, degenerative diseases of musculoskeletal system have not only medical significance but also social significance. Objective is studying the morphological features of synovial environment of the decompensated osteoarthritic (OA) knee joint. Structural features of subchondral bone, hyaline cartilage of the femur and tibia, the articular capsule, menisci and ligamentous apparatus of the knee joint were studied in 64 patients who underwent total knee arthroplasty at the Department of Traumatology and Orthopedics Bashkirian State Medical University in the period from 2015 to 2020. Material selection, preparation of histological samples, staining with hematoxylin-eosin, microscopy was performed. Adaptive signs of articular cartilage of the femoral condyles manifest in the form of cartilage tissue rearrangement, which are most pronounced in the central zone of the cartilage. At the same time, the phenomena of decompensation and significant areas of destruction are noted. Also, the subchondral bone was replaced with connective tissue with subsequent sclerosis. This sclerosis subsequently led to the decompensation of structures of the hyaline cartilage in the deep and middle zones. Destructive and dystrophic processes were noted in the knee joint menisci. Articular cartilage was replaced with granulation tissue with subsequent invasion of blood vessels. Cruciate ligaments in patients with OA show signs of adaptation due to expansion of endothenonium layers between bundles of collagen fibers and an increase in the diameter of blood vessels.

Abstract: The article discusses the features of biomimetics as a science that allows to suggest technologies for creating new technologies. Strange to relate, the man is a being completely unadapted to life. At the same time, man made a lot of discoveries precisely thanks to the observation of animals — from primitive tools based on the teeth of other animals to the first flying machines. Over time, the human civilization has defined a whole direction in science, which explores mechanisms in nature in order to use them for the benefit of man. With the help of biomimetics (from the Latin "bios" - life and "mimesis" - imitation), many problems from medicine, architecture, transport and energy were solved.

Abstract: The article considers the advances of biomedical engineering as the basis of scientific advances. Biomedical Engineering is the development and application of technical equipment for medical and biological research. This is an area where technologists, biologists and physicians work together to gain basic knowledge of the physical properties and behaviour of biological materials. The knowledge gained by these scientists is used to create devices, perform operations and develop new methods that improve human health and quality of life. Advances in biomedical technology made possible by this partnership include dialysis machines designed to replace sick and malfunctioning kidneys; hip and knee prostheses; materials and technologies for the work of the heart and blood vessels; artificial heart.

Abstract: The article discusses the advances of biomimetics in imitation of the laws of nature. Everything in nature is perfect. Nature is smart, rational and innovative, that’s why scientists and engineers from all over the world are trying to reproduce natural principles in the laboratory. The use of ideas borrowed from wildlife is called biomimetics. Since Leonardo da Vinci tried to design an airplane that simulates the flight of birds, the biomimetics - the science of using natural attributes, functions, and structures in technical equipment was first spoken about. Many scientists look to nature in the hope of finding solutions to the complex issues that humans face. In this regard, the nature provides many ready-made solutions - we just need to adapt them to specific technical problems.