Utilize Chitosan to Coat Hydroxyapatite on Polymer

Abstract:

Biocompatible bone implants are often proposed to improve osseointegration such as metal or polymer. Calcium hydroxyapatite Ca₁₀(PO₄)₆-OH₂, HA is the primary inorganic component of human bone. Hydroxyapatite and polymer are biocompatible to the human body and help to increase bone growth. Increasing osseointegration by application of coating polymer on ceramic using the dip coating method is a challenge in itself for the success of the process of coating polymeric materials on ceramic materials using the previous method. This research aims to establish a new interface for promoting osseointegration. This interface between the polymeric part and the bone tissue to overcome the problems and failures that occur in the metal limbs implanted in the amputees. As a result of its rejection by the cells of the living body or the lack of good cohesion between the implant and the place of contact. In this work, coat PEEK plastic material coated with an active biocompatible material (Hydroxyapatite). The polymeric parts that implant inside the bone will be used as an anchor for the metallic screw that is used for bone succession or artificial limb. This research is one of a series of investigations that enhance bone osseointegration in the simplest and most efficient method. The dipping method is used to create adhesive between ceramic and polymer (polyether ether ketone) depending on the chitosan material. Tape tests showed that there was good adherence between the HA and PEEK surfaces.

• Periodical: Journal of Biomimetics, Biomaterials and Biomedical Engineering (Volume 63)
• Pages: 1-10
• DOI: https://doi.org/10.4028/p-k17mEG
• Online since: November 2023
• Authors: Marwa Jamal Mohammed*, Marwan N. Arbilei, Sadiq J. Hamandi, Hussein A. Hussein
• Keywords: Chitosan, Coating, Haydroxyaptite, Imaplant, Osseointegration, Polyether Ether Ketone

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