Hybrid Graphene-Boron Nitride Nanobridges: A Multiscale Quantum Model for Enhanced Neural Tissue Regeneration

Abstract:

Nerve tissue regeneration represents a fundamental scientific challenge, especially in large spinal cord injuries inhibited by natural biological factors. The ability of peripheral nerves to spontaneously repair small injuries is limited, necessitating complex surgical grafts with secondary complications in larger cases. This research develops a revolutionary strategy based on hybrid nanobridges made from a scientifically proven combination of graphene (59%) and boron nitride (41%). Graphene provides ultrafast electrical conductivity (1.6 × 10⁶ m/s), while boron nitride ensures optimal biocompatibility (9.4/10) and mechanical stability. The results revealed that the optimal hybrid ratio increased the efficiency of nerve signal transmission by 40%, and increased the quantum tunneling probability to 0.65 at 3 nm, accelerating axonal regeneration. The high electric field concentration (0.1 V/nm) in the nucleus allows for precise stimulation of damaged cells. By combining the superior electrochemical properties of graphene with the optimal biocompatibility of boron nitride, these nanobridges represent a quantum leap in neural tissue engineering, opening new horizons for treating spinal paralysis and complex injuries.

• Periodical: Journal of Biomimetics, Biomaterials and Biomedical Engineering (Volume 73)
• Pages: 51-63
• DOI: https://doi.org/10.4028/p-xF3eWX
• Online since: July 2026
• Authors: Mundher Al-Shakban*
• Keywords: Hybrid Graphene-Boron Nitride, Nanobridges, Neural Tissue Regeneration

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