Apatite Deposition on Polyamide Film Containing Silanol Groups in Simulated Body Environment

Takahiro Kawai; Chikara Ohtsuki; Masanobu Kamitakahara; Masao Tanihara; Toshiki Miyazaki; Yoshimitsu Sakaguchi; Shigeji Konagaya

doi:10.4028/www.scientific.net/KEM.284-286.505

Paper Titles

Formation of Hydroxycarbonate Apatite Layer on Poly(Lactic Acid) Composites in Simulated Body Fluid
p.489

Using X-Ray Micro-CT Imaging to Monitor Dissolution of Macroporous Bioactive Glass Scaffolds
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Nanoscale Morphology of Apatite Precipitated onto Synthetic Hydroxyapatite from Simulated Body Fluid
p.497

A/W Bioactive Glass Particles in HEPES Solutions
p.501

Apatite Deposition on Polyamide Film Containing Silanol Groups in Simulated Body Environment
p.505

Accelerated Formation of Bone-Like Apatite on Biodegradable Polymer Substrates
p.509

Effect of Other Oxides on Solubility and Bioactivity in Calcium Phosphate Glasses
p.513

Conformational Change of Protein due to Contact with Bioceramic Materials
p.517

Activation of Hydroxyapatite Crystal Growth on the Surface of Biomimetic Synthetic Apatites through Electrical Polarization
p.521

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Apatite Deposition on Polyamide Film Containing Silanol Groups in Simulated Body Environment

Abstract:

Organic polymer coated with hydroxyapatite (so-called apatite) on its surface is a candidate of new hybrid materials for medical applications since it is expected to show bone-bonding ability and achieve mechanical properties derived from organic substrate. We have shown that some kinds of polyamide films containing carboxyl group or sulfonic group form hydroxyapatite in the simulated body environment, when they are incorporated with calcium chloride. In the present study, the polyamide containing carboxyl groups were modified with silanol groups and its apatite-forming ability was investigated in 1.5SBF, which has ion concentrations 1.5 times those of a simulated body fluid (SBF). It was found that polyamide films modified with silanol groups showed higher ability to induce apatite on its surface in 1.5SBF than the films without the modification, when they were incorporated with calcium chloride.