Physical Properties of Composite Membrane Containing Apatite and Poly-Lactic Acid /Poly-Glycolic Acid Copolymer In Vitro
The purpose of this study was to evaluate the physical properties of the composite membrane before and after soaking in simulated body fluid (SBF) and discuss both degradation and maintenance of their properties. Before and after soaking in SBF, some deposits were found on the preexisted apatite crystals, and Ca and P were mainly detected by energy dispersive X-ray analyzer (EDX). Our results suggest that the composite membrane consisting of apatite and the biodegradable PLGA copolymer would have excellent biocompatibility and maintain adequate physical properties for in vivo use.
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
T. Watanabe et al., "Physical Properties of Composite Membrane Containing Apatite and Poly-Lactic Acid /Poly-Glycolic Acid Copolymer In Vitro ", Key Engineering Materials, Vols. 284-286, pp. 749-752, 2005