Bone-Bonding Ability of Ce-TZP/Al2O3 Nanocomposite with a Microporous Surface and Calcium Phosphate Coating

Mitsuru Takemoto; Shunsuke Fujibayashi; J. Suzuki; Tadashi Kokubo; Takashi Nakamura

doi:10.4028/www.scientific.net/KEM.284-286.987

Paper Titles

Polyethylene Wear Against Alumina and Zirconia Heads in K-Max Total Hip Arthroplasty
p.971

Safety Issues in the Use of THR Ceramic Heads and Cups
p.975

Alumina Matrix Composites in Arthroplasty
p.979

ATZ – A New Material with a High Potential in Joint Replacement
p.983

Bone-Bonding Ability of Ce-TZP/Al₂O₃ Nanocomposite with a Microporous Surface and Calcium Phosphate Coating
p.987

Phase Stability of Zirconia and Alumina/Zirconia Composite Heads against UHMWPE Liners in a Temperature-Controlled Hip Simulation Study
p.991

Third-Body-Wear as a Risk Factor in Joint Endoprosthetics
p.995

Investigation of Monoclinic Content on Clinically Retrieved Zirconia Heads
p.999

Ceramic-On-Ceramic Implants in Total Hip Arthroplasty
p.1003

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Bone-Bonding Ability of Ce-TZP/Al₂O₃ Nanocomposite with a Microporous Surface and Calcium Phosphate Coating

Abstract:

The nano-composite of a ceria-stabilized tetragonal zirconia polycrystals (Ce-TZP) and alumina (Al2O3) polycrystals (Ce-TZP/Al2O3) is attractive as a load-bearing bone substitute because of its mechanical properties and phase stability. We have developed a new method of hydrofluoric acid and heat treatment (HFT) to give a microporous structure to the surface of this Ce-TZP/Al2O3 nanocomposite ceramic. Bone-bonding ability of a microporous surface and calcium phosphate coating on Ce-TZP/Al2O3 composite has been investigated through in vivo detaching model. Thin calcium phosphate coating layer was added by alternate soaking process, and thick CaP layer was produced by soaking in simulated body fluid for 5 days. HFT treated Ce-TZP/Al2O3 composite showed high bone-bonding ability compared with the control group. Thick and thin CaP coating accelerated bone-bonding ability in early post-implantation period. The submicron microporous surface was beneficial for achieving mechanical interlocking between the ceramic and surrounding bone. These results suggest the possibility of using a Ce-TZP/Al2O3 nanocomposite ceramic with microporous surface and calcium phosphate coating as the bearing material for uncemented total joint replacements.