Glucosamine Coating for Inhibiting Bacterial Adhesion to Titanium Surfaces

Yuehuei H. An; Melissa Farino; Qian K. Kang; Marina V. Demcheva; John Vournakis

doi:10.4028/www.scientific.net/KEM.288-289.343

Paper Titles

Blood Compatibility of Chitosan Immobilized on Poly(Ethylene Terephthalate) Surface Modified by Plasma and Ultraviolet Grafting
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Surface Characterization and Antibacterial Evaluation of Poly(Ethylene Terephthalate) Modified by Chitosan-Immobilization
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Nitrogen Plasma Source Ion Implantation (PSII) for Improvement of Blood-Compatibility of Silicon
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Hemocompatibility of PET (Polyethylene Terephthalate) Films Grafted PEG (Polyethylene Glycol) by Plasma Surface Modification
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Glucosamine Coating for Inhibiting Bacterial Adhesion to Titanium Surfaces
p.343

Physico-Chemical Modifications and Biological Improvements of Biomedical PET as a Consequence of Excimer LASER Irradiation
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Effect of Rare Earth Y₂O₃ Content on Microstructure of Gradient Bioceramic Composite Coating Produced by Wide-Band Laser Cladding
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The Mechanical Behavior of Water Vapor-Treated HA Coating Produced by Plasma Spraying Technique
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Comparison in In Vitro Evaluation of Wollastonite and Dicalcium Silicate Coatings
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Glucosamine Coating for Inhibiting Bacterial Adhesion to Titanium Surfaces

Abstract:

It is known that glucosamine/chitosan derivatives have the ability of inhibiting bacterial adhesion to tooth and biomaterial surfaces. The hypotheses of this article included 1) the inhibition effects of different (chemically) glucosamine products are different and 2) more water-soluble glucosamine preparation(s) may have a superior inhibition effect. The basic testing systems are in vitro static adhesion models and the amount of the adhesion is evaluated by direct counting using epifluorecense microscopy. The test material is a smooth surfaced commercially pure titanium (cp-Ti). The bacterium tested is Staphylococcus aureus. The results showed that compared to the control samples (without glucosamine or chitosan coating) the sulfated p-GlcNAc and Sigma glucosamine HCl significantly inhibited S. aureus adhesion to titanium surfaces (94% and 78% respectively)