Glucosamine Coating for Inhibiting Bacterial Adhesion to Titanium Surfaces

Abstract:

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It is known that glucosamine/chitosan derivatives have the ability of inhibiting bacterial adhesion to tooth and biomaterial surfaces. The hypotheses of this article included 1) the inhibition effects of different (chemically) glucosamine products are different and 2) more water-soluble glucosamine preparation(s) may have a superior inhibition effect. The basic testing systems are in vitro static adhesion models and the amount of the adhesion is evaluated by direct counting using epifluorecense microscopy. The test material is a smooth surfaced commercially pure titanium (cp-Ti). The bacterium tested is Staphylococcus aureus. The results showed that compared to the control samples (without glucosamine or chitosan coating) the sulfated p-GlcNAc and Sigma glucosamine HCl significantly inhibited S. aureus adhesion to titanium surfaces (94% and 78% respectively)

Info:

Periodical:

Key Engineering Materials (Volumes 288-289)

Edited by:

Xingdong Zhang, Junzo Tanaka, Yaoting Yu and Yasuhiko Tabata

Pages:

343-346

DOI:

10.4028/www.scientific.net/KEM.288-289.343

Citation:

Y. H. An et al., "Glucosamine Coating for Inhibiting Bacterial Adhesion to Titanium Surfaces", Key Engineering Materials, Vols. 288-289, pp. 343-346, 2005

Online since:

June 2005

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Price:

$35.00

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