Apatite Formation Behavior on Tricalcium Phosphate (TCP) Porous Body in a Simulated Body Fluid
Apatite formation behavior of tricalcium phosphate (TCP) ceramics with different phases and porosity was investigated in a simulated body fluid (SBF, Kokubo solution). The pure α-TCP with 80% porosity did not form hydroxyapatite (HAp) on its surface after soaking in SBF for 7 days. On the other hand, the pure α-TCP with 20% porosity formed HAp on its surface after soaking in SBF within 7 days, and the biphasic TCP, which consisted of mixture of α-TCP and β-TCP and had 20% porosity, formed HAp within 1 day. The low porosity and coexistence of α-TCP and β-TCP phases in TCP ceramics were effective for apatite formation in SBF.
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
T. Uchino et al., "Apatite Formation Behavior on Tricalcium Phosphate (TCP) Porous Body in a Simulated Body Fluid", Key Engineering Materials, Vols. 309-311, pp. 251-254, 2006