The Analysis of Osteoconducting Ability of Alpha-Tricalcium Phosphate-Based Bone Filler Powder

Abstract:

Article Preview

Titanium alloy(Ti-6Al-4V, Samsung techwin, Korea) rods with diameter of 2.5mm were used as the implant materials. Polymethyl methacrylate(PMMA) bone cements(CMW, USA) were used as bone cement and -tricalcium phosphate(TCP)-based bone filler powder was used as osteoconductive additives. Hydroxyapatite(HA) was the desired end product after hydrolysis of the -TCP-based bone filler powder mixed with the blood. In animal study using rabbits, we divided the group into A, B, C and D. Rabbits were sacrificed at 1, 3, 9 weeks after implantation and the affinity index and bone density were calculated. X-ray diffraction patterns of HA formed by hydrolysis of -TCP-based bone filler powder showed higher and higher intensity in HA peak with increase of time period. There was more bone density increase in the group B and D containing - TCP-based bone filler powder around implant site than in the group A and C(p<0.05). It is suggested that HA formed by hydrolysis of -TCP-based bone filler powder will play some parts in enhancing osteconducting ability in clinical settings.

Info:

Periodical:

Key Engineering Materials (Volumes 309-311)

Main Theme:

Edited by:

Takashi Nakamura, Kimihiro Yamashita and Masashi Neo

Pages:

259-262

DOI:

10.4028/www.scientific.net/KEM.309-311.259

Citation:

J. H. Yoo et al., "The Analysis of Osteoconducting Ability of Alpha-Tricalcium Phosphate-Based Bone Filler Powder", Key Engineering Materials, Vols. 309-311, pp. 259-262, 2006

Online since:

May 2006

Export:

Price:

$35.00

In order to see related information, you need to Login.

In order to see related information, you need to Login.