In Vitro Bioactivity of Bi-Structured Nano-Hybrids in the CaO-SiO2-PTMO System

Abstract:

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Synthetic model of a large transparent crack-free monolithic ceramic-polymer hybrid, which was synthesized using triethoxysilane end-capped poly(tetramethylene oxide) (Si-PTMO) and tetraethoxysilane (TEOS), was examined in the CaO-SiO2-PTMO sol-gel system. Bulk precursor with nominal mass ratio of PTMO: TEOS = 80: 20 and surface precursor with nominal molar ratio of TEOS: Ca(NO3)2 = 1: 0.3 were subjected to hybridization through hydrolysis and condensation process, producing a bi-structured hybrid in which polymeric bulk was molecular hybridized with bioactive silicate surface. Spectroscopic and microscopic characterizations revealed that the surface of hybrid was typical bioactive silicate. In vitro study using a simulated body fluid (SBF) revealed that the hybrid formed an apatite on its surface within 6 hours in SBF, suggesting bioactive materials with high capability of tissue integration as well as polymeric physical properties.

Info:

Periodical:

Key Engineering Materials (Volumes 309-311)

Main Theme:

Edited by:

Takashi Nakamura, Kimihiro Yamashita and Masashi Neo

Pages:

549-552

DOI:

10.4028/www.scientific.net/KEM.309-311.549

Citation:

M.-Y. Koh et al., "In Vitro Bioactivity of Bi-Structured Nano-Hybrids in the CaO-SiO2-PTMO System", Key Engineering Materials, Vols. 309-311, pp. 549-552, 2006

Online since:

May 2006

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Price:

$35.00

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