FBG sensors have excellent compatibility with CFRP sheets. It can be embedded into CFRP sheets to fabricate the “smart” CFRP. This paper conducted 4 pieces of CFRP-strengthened RC beams, and embedded FBG sensors and strain gauges on the steel, concrete and CFRP of RC beams. The simulation program of flexural load effects of RC beams is compiled based on the theory of reinforced concrete and ANSYS. The experimental results show that during the load bearing process: the compatibility is perfect between FBG sensor and CFRP; the linear relationship of FBG sensor and strain gauge is uniform; the numerical simulation results and the measuring results of strains of tensile steel and compressive concrete, the load agree well. So utilizing the smart CFRP strengthened RC structures can realize the dual function of advanced rehabilitation and real-time health monitor and evaluation.