Gene Expression Profile of Osteoblast-Like Cells on Calcium Phosphate Biomaterials
Gene expression profile of osteoblast-like cells cultured on dense disk materials and porous materials of calcium phosphate ceramics was constructed from DNA microarray analyses. The profile revealed that gene expression patterns of porous materials were significantly different from those of dense disk materials. The porous materials had a capacity to induce expressions of genes involved in osteoblast differentiation, while dense disk materials regulated gene expressions related to osteoclastogenesis.
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
T. Takemura et al., "Gene Expression Profile of Osteoblast-Like Cells on Calcium Phosphate Biomaterials", Key Engineering Materials, Vols. 330-332, pp. 1087-1090, 2007