Gene Expression Profile of Osteoblast-Like Cells on Calcium Phosphate Biomaterials

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Abstract:

Gene expression profile of osteoblast-like cells cultured on dense disk materials and porous materials of calcium phosphate ceramics was constructed from DNA microarray analyses. The profile revealed that gene expression patterns of porous materials were significantly different from those of dense disk materials. The porous materials had a capacity to induce expressions of genes involved in osteoblast differentiation, while dense disk materials regulated gene expressions related to osteoclastogenesis.

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Key Engineering Materials (Volumes 330-332)

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1087-1090

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February 2007

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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