Preliminary Study on the Biocompatibility of Calcium Phosphate Bone Cement Containing N,O-Carboxymethyl Chitosan

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N,O-carboxymethyl chitosan (CMCTS) was added in Calcium phosphate bone cement (CPC). A preliminary study was carried out in order to evaluate the biocompatibility of CPC containing CMCTS. In vitro tests were done using extract liquid from normal saline. The result showed that the biological reaction complied with standards of GB/16886 and the composite might have good biocompatibility.

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Periodical:

Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu

Pages:

807-810

Citation:

Q. Huang et al., "Preliminary Study on the Biocompatibility of Calcium Phosphate Bone Cement Containing N,O-Carboxymethyl Chitosan", Key Engineering Materials, Vols. 330-332, pp. 807-810, 2007

Online since:

February 2007

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$38.00

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[4] Biological evaluation of medical devices-Part 12: Sample preparation and reference materials. GB/T 16886. 12-(2005).

[5] Biological evaluation of medical devices-Part 11: Tests for systemic toxicity. GB/T 16886. 11-(1997).

[6] Equipment for medical use-Part 2: Biological test methods. GB/T 14233. 2-(2005).

[7] Biological evaluation of medical devices-Part 10: Tests for irritation and delayed-type hypersensitivity. GB/T 16886. 10-(2005).

[8] Biological evaluation of medical devices-Part 4: Selection of tests for interactions with blood. GB/T 16886. 4-(2003).

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