Bimodal Porous Bi-Phasic Calcium Phosphate Ceramics and Its Dissolution in SBF Solution


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Biphasic calcium phosphate (BCP) ceramics, a mixture of hydroxyapatite (HAp) and beta-tricalcium phosphate (β-TCP), of varying HAp/β-TCP ratios were prepared from fine powders. Porous BCP ceramic materials with HAp/β-TCP weight rations of 20/80, 40/60, and 80/20 were prepared. In this study, the bioactivity is reduced at a larger HAp content rate, which is likely related to the high driving pore for the formation of a new phase, and the reaction rate was proportional to the β-TCP. The porous BCP ceramics having a bigger porosity rate can easily under up dissolution. The powder having a larger β-TCP content rate can easily generate a new phase. The dissolution results confirmed that the biodegradation of calcium phosphate ceramics could be controlled by simply adjusting the amount of HAp or β-TCP in the ceramics and porosity rate.



Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu




Y. Zhang et al., "Bimodal Porous Bi-Phasic Calcium Phosphate Ceramics and Its Dissolution in SBF Solution", Key Engineering Materials, Vols. 330-332, pp. 91-94, 2007

Online since:

February 2007




[1] L.L. Hench and J. Wilson: World Scientific, London, UK (1993).

[2] C.P.A.T. Klein, A.A. Driessen, K. Groot and A. de Hooff:J. Biomed. Mater. Res. 17(1983), p.769.

[3] D. S. Metsger, T. D. Driskell and J. R. Paulstrud: J. Am. Dent. Assoc. 105(1982), p.1035.

[4] R. Z. Legeros: Adv. Dent. Res. 2(1988), p.164.

[5] R. F. Ellinger, E. B. Nery and K. L. Lynch: Int. J. Periodont. Restor. Dent. 3(1986), p.223.

[6] N. Passuti and G. Daculsi: Presse Med. 18(1989), p.28.

[7] A. Takeishi, H. Hayashi, H. Kamatsubara, A. Yokoyama, M. Kohri, K. Miki and T. Kohgo: J. Dent. Res. 68(1989), p.680.

[8] C.T. Laurencin, A.M.A. Ambrosio, M.D. Borden and J.A. Cooper, Tissue engineering: orthopedic applications, Annu Rev Biomed Eng 1 (1999), p.19.


[9] Y. Zhang, Y. Yokogawa and T. Kameyama: J. Key Eng. Mater. 280-283(2005), p.1571.

[10] Y. Zhang, Y. Yokogawa, and T. Kameyama. Key Eng. Mater. 317-318(2006), p.723.

[11] Y. Zhang,Y. Yokogawa andT. Kameyama. Adv. Mater. Res. Vol. 11-12 (2006), p.227.