Two Dimensional Histogram of X-Ray Microtomogrpahy and Its Application in Quantification of Ex Vivo Implants

Abstract:

Computerized X-ray microtomography (micro CT) is a powerful technique for imaging and quantification in biomedical materials research. Mapping of various tissue/implants in 3-dimension, which is not achievable with traditional histological slices, is particularly desirable in ex-vivo implant analysis. However, due to a variety of artifacts during image formation, especially the blurred interfaces due to the machine contrast transfer function and the partial volume effect, quantification based on traditional histograms is not accurate. In this work we propose a new 2-dimensional histogram and its application in the analysis of micro CT data of ex-vivo implants, which significantly improve the clarity of the definition of different phases and drastically reduced the artifacts of segmentation compared to conventional methods.

• Periodical: Key Engineering Materials (Volumes 330-332)
• Pages: 915-1918
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.330-332.915
• Online since: February 2007
• Authors: Shuo Zou, Roger A. Brooks, Serena Best, Tom Buckland, Xiao Wei Fu, Neil Rushton, William Bonfield
• Keywords: Ex Vivo Implant, Quantification, Segmentation, X-Ray Microtomography

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