A Study of Osteocalcin Production In Vitro on Various Hydroxyapatite Based Biomaterials

J.L. Xu; Khiam Aik Khor; W.N. Chen

doi:10.4028/www.scientific.net/KEM.330-332.897

Paper Titles

Effect of Mn on Protein Adsorption on Mn-TCP/FHA Coatings
p.881

Effect of Pamidronate on Protein Adsorption and Osteoblast Adhesion to Hydroxyapatite Bioceramics Scaffold
p.885

Behaviors of Platelets Adherent on Si-N(H) Surface Prepared from Ammonia Plasma-Implanted Silicon
p.889

Study of Protein Adsorption and Conformational Change on DLC and Ti Surfaces Using FTIR and Coomassie Brilliant Blue Protein Assay
p.893

A Study of Osteocalcin Production In Vitro on Various Hydroxyapatite Based Biomaterials
p.897

Studies on Characteristics and Adsorption of BSA on Hydrogel Biomaterials
p.901

Fabrication and Mechanical Properties of Dense/Porous β-Tricalcium Phosphate Bioceramics
p.907

Segementation of X-Ray Microtomography Data of Porous Scaffold
p.911

Two Dimensional Histogram of X-Ray Microtomogrpahy and Its Application in Quantification of Ex Vivo Implants
p.915

HomeKey Engineering MaterialsKey Engineering Materials Vols. 330-332A Study of Osteocalcin Production In Vitro on...

A Study of Osteocalcin Production In Vitro on Various Hydroxyapatite Based Biomaterials

Abstract:

Hydroxyapatite based biomaterials were prepared by a spark plasma sintering technology. The human limb-derived osteoblasts were cultured on the various biomaterial surfaces (HA, RF21, 1SiHA and 5SiHA) for up to two weeks to investigate the cellular behaviors. The bone gammacarboxyglutamic protein or osteocalcin in the medium were determined at different periods of cell culture. The results indicated that a combined effect of bioceramic surface composition and surface morphology had influenced the osteoblast behaviors. The amount of osteocalcin in the medium increased in the initial periods of culture but decreased in the late periods of culture.

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Periodical:

Key Engineering Materials (Volumes 330-332)

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897-900

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.330-332.897

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Online since:

February 2007

Authors:

J.L. Xu, Khiam Aik Khor, W.N. Chen

Keywords:

Hydroxyapatite (HAP), In Vitro, Osteocalcin, Spark Plasma Sintering (SPS)

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