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Microstructure and Properties of A Calcium Phosphate Cement Tissue Engineering Scaffold Modified with Collagen and Chitosan

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Abstract:

In this study, an ACP-DCPD based Calcium phosphate cement (CPC) scaffold with a porosity of 88% was prepared by using Na3PO4 as a poregen and then modified by collagen and chitosan. The results showed that collagen and chitosan obviously increased the compressive strength. Cell culture showed that the cell can migrate, attach, proliferate and differentiate on the surface of the materials and the pores walls. This CPC scaffold modified with collagen or chitosan was a promising material to be used in bone tissue engineering.

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Periodical:

Key Engineering Materials (Volumes 330-332)

Pages:

983-986

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.330-332.983

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Online since:

February 2007

Authors:

Xiu Peng Wang, Jian Dong Ye, Ling Chen, Ying Jun Wang

Keywords:

Calcium Phosphate Cement (CPC), Chitosan (CS), Collagen, Tissue Engineering Scaffold

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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