Microstructure and Properties of A Calcium Phosphate Cement Tissue Engineering Scaffold Modified with Collagen and Chitosan
In this study, an ACP-DCPD based Calcium phosphate cement (CPC) scaffold with a porosity of 88% was prepared by using Na3PO4 as a poregen and then modified by collagen and chitosan. The results showed that collagen and chitosan obviously increased the compressive strength. Cell culture showed that the cell can migrate, attach, proliferate and differentiate on the surface of the materials and the pores walls. This CPC scaffold modified with collagen or chitosan was a promising material to be used in bone tissue engineering.
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
X. P. Wang et al., "Microstructure and Properties of A Calcium Phosphate Cement Tissue Engineering Scaffold Modified with Collagen and Chitosan", Key Engineering Materials, Vols. 330-332, pp. 983-986, 2007